Evaluation of methods for detecting substance use disorder in persons with severe mental illness.

Wolford, George; Rosenberg, Stanley D.; Drake, Robert E.; Mueser, Kim T.; Oxman, Thomas E.; Hoffman, Douglas; Vidaver, Robert M.; Luckoor, Ravindra; Carrieri, Karen L.

doi:10.1037/0893-164x.13.4.313

Cited by 73 publications

(65 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Self-report regarding substance use in persons with severe mental illness, especially using the ASL may be suspect for a variety of reasons (Goldfinger et al 19%;Carey et al 1997;Wolford et al 1999), but the TLFB has been shown to be a reliable and valid measure in this population (Carey 1997). For the analyses of alcohol and drug use outcomes in this study, we therefore used both self-report based on the TLFB and multimodal ratings of severity.…”

Section: Methodsmentioning

confidence: 99%

The Effects of Clozapine on Alcohol and Drug Use Disorders Among Patients With Schizophrenia

Drake

Xie

McHugo

et al. 2000

Schizophrenia Bulletin

236

123

View full text Add to dashboard Cite

Several case studies indicate that clozapine use is associated with reductions in the use of nicotine, alcohol, or illicit drugs. Although not designed to assess clozapine, this study explored a posteriori the effects of clozapine on alcohol and drug use disorders among schizophrenia patients. Among 151 patients with schizophrenia or schizoaffective disorder and co-occurring substance use disorder who were studied in a dual-disorder treatment program, 36 received clozapine during the study for standard clinical indications. All participants were assessed prospectively at baseline and every 6 months over 3 years for psychiatric symptoms and substance use. Alcohol-abusing patients taking clozapine experienced significant reductions in severity of alcohol abuse and days of alcohol use while on clozapine. For example, they averaged 54.1 drinking days during 6-month intervals while off clozapine and 12.5 drinking days while on clozapine. They also improved more than patients who did not receive clozapine. At the end of the study, 79.0 percent of the patients on clozapine were in remission from alcohol use disorder for 6 months or longer, while only 33.7 percent of those not taking clozapine were remitted. Findings related to other drugs in relation to clozapine were also positive but less clear because of the small number of patients with drug use disorders. This study was limited by the naturalistic design and the lack of prospective, standardized measures of clozapine use. The use of clozapine by patients with co-occurring substance disorders deserves further study in randomized clinical trials.

show abstract

Section: Methodsmentioning

confidence: 99%

The Effects of Clozapine on Alcohol and Drug Use Disorders Among Patients With Schizophrenia

Drake

Xie

McHugo

et al. 2000

Schizophrenia Bulletin

236

123

View full text Add to dashboard Cite

show abstract

“…12, 13 They have previously been effectively applied in various psychiatric populations. [14][15][16][17][18][19] Although some of these studies involved heterogeneous populations of psychiatric patients, including those diagnosed with schizophrenia, only the AUDIT has been previously applied specifically to a population with schizophrenia. 15,20 One study employed the AUDIT in patients at the first to the third psychotic episode and found it to have a high sensitivity and specificity when the standard cut-off of 8 was used.…”

mentioning

confidence: 99%

Validation of the Alcohol Use Disorders Identification Test and the Drug Abuse Screening Test in First Episode Psychosis

2008

View full text Add to dashboard Cite

W La Revue canadienne de psychiatrie, vol 53, no 1, janvier 2008 26 Objective: To determine the validity and reliability of the Alcohol Use Disorders Identification Test (AUDIT) and Drug Abuse Screening Test (DAST) for detecting alcohol and drug use disorders, respectively, in a population with first-episode psychosis (FEP). Method:Subjects with FEP completed the AUDIT and DAST and were divided into groups according to the presence or absence of a Structured Clinical Interview for DSM-IV (SCID) diagnosis of either current alcohol or drug misuse. The data were analyzed to see whether AUDIT and DAST scores were predictive of SCID diagnosis. Results:Patients with alcohol-related SCID diagnoses and those with drug-related SCID diagnoses scored significantly higher on the AUDIT and DAST, respectively, than the group without the respective SCID diagnosis (P < 0.001 in both cases). The AUDIT functioned best with a problem drinking cut-off score of 10 (sensitivity, 85%; specificity, 91%). The DAST functioned best with a problem drug use cut-off score of 3 (sensitivity, 85%; specificity, 73%). The area under the receiver operating characteristic curve was 0.86 for the AUDIT and 0.83 for the DAST. Conclusion:The DAST and AUDIT may reliably identify FEP patients with substance abuse. Can J Psychiatry 2007;53(1):26-33Information on funding and support and author affiliations appears at the end of the article. Clinical Implications· Given the efficacy of the AUDIT and DAST in patients with FEP, clinicians should be able to screen for substance use disorders quickly and regularly, with minimal burden on resources. · This might promote better monitoring of substance use disorders in this population, which is prone to adverse consequences from such use. · These instruments function better in a population with FEP when cut-off scores are altered to better suit this population. Limitations· AUDIT cut-off points are less precise because there were few subjects with problem drinking. A slightly larger sample might have helped in this regard. · One-third of the total catchment area sample either refused treatment and (or) refused consent to participate in this study, limiting somewhat the generalizability of these findings. Data analyzed derived solely from scores on the AUDIT and DAST administered to patients at baseline. Other time points in treatment were not examined.

show abstract

“…The abuse and dependence sections of the English version of MINI have previously been used as reference standards in a study validating RAFFT [48,49]. Although all measures were based on the patients' self-report, previous studies have indicated that severely mentally ill patients provide reliable information about their drug use [50,51]. …”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Alcohol Use Disorders Identification Test and the Drug Use Disorders Identification Test among Patients at a Norwegian Psychiatric Emergency Ward

Gundersen¹,

Mordal²,

Berman

et al. 2013

Eur Addict Res

View full text Add to dashboard Cite

High rates of substance use disorders (SUD) among psychiatric patients are well documented. This study explores the usefulness of the Alcohol Use Disorders Identification Test (AUDIT) and the Drug Use Disorders Identification Test (DUDIT) in identifying SUD in emergency psychiatric patients. Of 287 patients admitted consecutively, 256 participants (89%) were included, and 61-64% completed the questionnaires and the Mini-International Neuropsychiatric Interview (MINI), used as the reference standard. Both AUDIT and DUDIT were valid (area under the curve above 0.92) and reliable (Cronbach's alpha above 0.89) in psychotic and nonpsychotic men and women. The suitable cutoff scores for AUDIT were higher among the psychotic than nonpsychotic patients, with 12 versus 10 in men and 8 versus 5 in women. The suitable cutoff scores for DUDIT were 1 in both psychotic and nonpsychotic women, and 5 versus 1 in psychotic and nonpsychotic men, respectively. This study shows that AUDIT and DUDIT may provide precise information about emergency psychiatric patients' problematic alcohol and drug use.

show abstract

Evaluation of methods for detecting substance use disorder in persons with severe mental illness.

Cited by 73 publications

References 35 publications

The Effects of Clozapine on Alcohol and Drug Use Disorders Among Patients With Schizophrenia

The Effects of Clozapine on Alcohol and Drug Use Disorders Among Patients With Schizophrenia

Validation of the Alcohol Use Disorders Identification Test and the Drug Abuse Screening Test in First Episode Psychosis

Evaluation of the Alcohol Use Disorders Identification Test and the Drug Use Disorders Identification Test among Patients at a Norwegian Psychiatric Emergency Ward

Contact Info

Product

Resources

About