Evaluation of microcirculatory disturbances in patients with rheumatic diseases by the method of diffuse reflectance spectroscopy

Monitoring oxidative metabolism while modeling pancreatic ischemia in mice using a multimodal spectroscopy technique

“…The degree of blood oxygen saturation in tissue (tissue saturation) can be determined using reflection coefficients at the wavelengths corresponding to the isobestic and nonisobestic points of oxy-and deoxyhemoglobin by the following equation [24][25][26]:…”

Laser Doppler Spectrum Analysis Based on Calculation of Cumulative Sums Detects Changes in Skin Capillary Blood Flow in Type 2 Diabetes Mellitus

“…Optical, non-invasive diagnostics offer a good range of methods for the evaluation of the functional insufficiency in the components of tissue vitality including blood microcirculation system. The methods are based on such approaches as fluorescence spectroscopy [ 6 ], diffuse reflectance spectrocopy [ 7 , 8 , 9 ], speckle contrast imaging [ 10 ], photopletismography [ 11 ], videocapillaroscopy [ 12 ] and methods based on coherent light scattering and optical coherence tomography [ 13 , 14 ].…”

Influence of Melanin Content on Laser Doppler Flowmetry and Tissue Reflectance Oximetry Signal Formation

“…The tissue reflectance oximetry method provides information about the tissue oxygen saturation (StO2) of the examined biological tissue microcirculation and allows for calculation of the relative blood volume (Vb) in the surface layers of soft tissues (skin, mucous membranes). This technology is based on the difference in the optical properties of oxygenated (HbO2) and deoxygenated (Hb) haemoglobin when irradiated with green and red light [7][8][9]. Furthermore, in conjunction with LDF and other optical methodologies, tissue oximetry is a powerful tool capable of providing non-invasive measurements of parameters such as oxygen consumption within a living tissue.…”