Evaluation of Montreal cognitive assessment for the differential diagnosis of mild cognitive impairment and Alzheimer’s disease in elderly patients with more than 5 years of schooling: Data from a Brazilian sample

Montiel, José María; Cecato, Juliana Francisca; Bartholomeu, Daniel; Martinelli, José Eduardo

doi:10.4236/aar.2013.24018

Cited by 8 publications

(6 citation statements)

References 23 publications

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“…To our knowledge, though, the utility of this tool in the context of MCI remains unknown. Previous studies indicate that the Montreal Cognitive Assessment (MoCA) [44], a screening tool for global cognition, can distinguish MCI from HC and early stage AD patients [45,46]. Can EF, as assessed with the IFS, also distinguish MCI from the other groups?…”

Section: Introductionmentioning

confidence: 99%

Distinguishing mild cognitive impairment from healthy aging and Alzheimer’s Disease: The contribution of the INECO Frontal Screening (IFS)

et al. 2019

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Executive functions are affected differently in healthy aging, Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD), and evaluating them is important for differential diagnosis. The INECO Frontal Screening (IFS) is a brief neuropsychological screening tool, developed to assess executive dysfunction in neurodegenerative disorders. Goals: We aimed to examine whether and how MCI patients can be differentiated from cognitively healthy controls (HC) and mild to moderate AD patients based on IFS performance. We also explored how IFS scores are associated with age, years of education, and depressive/anxious symptoms (as assessed by the Hospital Anxiety and Depression Scale). Method: IFS total scores were compared between 26 HC, 32 MCI and 21 mild to moderate AD patients. The three groups were matched for age and education. The Area Under the Curve (AUC) was analyzed and optimal cut-offs were determined. Results: Healthy participants had higher IFS scores than both clinical groups, and MCI patients had higher scores than AD patients. IFS showed high diagnostic accuracy for the detection of MCI (AUC = .89, p < .001) and AD (AUC = .99, p < .001), and for the differentiation between the clinical groups (AUC = .76, p < .001). We provide optimal cut-offs for the identification of MCI and AD and for their differentiation. We also found that, in general, higher education predicted higher IFS scores (no associations with age and depressive/anxious symptoms were observed). Altogether, these findings indicate that evaluating executive functions with the IFS can be valuable for the identification of MCI, a high-risk group for dementia, and for differentiating this condition from healthy aging and AD.

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Section: Introductionmentioning

confidence: 99%

Distinguishing mild cognitive impairment from healthy aging and Alzheimer’s Disease: The contribution of the INECO Frontal Screening (IFS)

et al. 2019

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“…We believe this is the case because clients under milder cognitive impairment have the attention and executive function to be more engaged in more complex activities, including those that require collaborative skills. Indeed, lower MoCA scores are expected in clients with more severe MCI ( Chiu et al, 2018 ; Damian et al, 2011 ; Gluhm et al, 2013 ; Ismail et al, 2010 ; Montiel et al, 2013 ; Pan et al, 2012 ; Trzepacz et al, 2015 ; Wang et al, 2013 ; Yeung et al, 2014 ), and the inability for these clients to perform basic tasks in MoCA will in turn, translate to reduced activity engagement and quicker need to transition to a variety of activities to stimulate their participation.…”

Section: Discussionmentioning

confidence: 99%

“…The most widely utilized tests to assess for impairment include a) Mini-Mental State Examination (MMSE) and b) Montreal Cognitive Assessment (MoCA). However, MoCA has been suggested to more effectively measure cognitive performance when taking into account repeated measures in decadal age increments ( Gluhm et al, 2013 ; Yeung et al, 2014 ), education ( Wang et al, 2013 ), ceiling effects ( Trzepacz et al, 2015 ) (MoCA 18% vs. MMSE 71%), and higher sensitivity in detecting MCI ( Damian et al, 2011 ; Ismail et al, 2010 ; Montiel et al, 2013 ; Pan et al, 2012 ). This in turn has led to greater reliance on MoCA and its variants (i.e., Hong Kong MoCA or HK-MoCA) which mitigates aforementioned issues within MMSE while effectively differentiating between healthy and MCI clients with greater sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Play Intervention for Dementia (PID) Activities in Addressing Cognitive Domains Reflected in Hong Kong Montreal Cognitive Assessment (HK-MoCA)

Yung

Tsang

2022

Gerontology and Geriatric Medicine

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Background/Objectives: Yee Hong Play Intervention for Dementia (PID) is a community program strengthening East Asians >65 years with dementia in their daily functional activities. We analyzed how PID activities align with Hong Kong Montreal Cognitive Assessment. Methods: Utilizing observation sheets procured from documentation notes from the twice-weekly PID sessions, cognitive domains were identified. Mean time duration and activity frequencies were compared between high and low competency client groups. Results: Independent of competency group, activities predominantly targeted attention/concentration (23.8% HC, 16.4% LC), and hand-eye coordination (19.1% HC, 28.7% LC). Less focused domains were delayed recall (3.1–4.7%) and naming (1.3–1.5%). Conclusions: Yee Hong PID tested innovative cognitive domains not currently covered in HK-MoCA screening assessment, emphasizing attention/concentration-oriented activities and none assessing orientation and language domains. Additionally, presence of new domains such as hand-eye coordination and fine motor dexterity suggested that strict adherence with standardized screening tools (e.g., MoCA) may not be ideal. Likely, facilitators have developed innovative measures to assess individual competency to strengthen resilience in our geriatric population.

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“…Além disso, a sensibilidade para detectar casos de demência com MoCA foi de 100% (NASREDDINE et al, 2005). Dados semelhantes foram encontrados para o Brasil, com resultados mostrando o MoCA como melhor que o MEEM para diferenciar demência dos casos de CCL (CECATO et al, 2014;MONTIEL et al, 2013). Não existem dados sobre as qualidades psicométricas do MoCA para populações de baixa escolaridade.…”

Section: Instrumentos Breves De Rastreamento De Transtorno Neurocogniunclassified

“…Isso é esperado, já que a natureza das tarefas e a forma de avaliações são também diferentes entre os instrumentos. Isso pode favorecer um ou outro instrumento a ser mais adequadas na discriminação dos TNC(MONTIEL et al, 2013).Deste modo, os autores desenvolveram uma nova versão do MoCA, chamada de MoCA basic, substituindo os itens da versão anterior que mais dependiam da escolaridade por tarefas independentes de alfabetização e que mediam a mesma função cognitiva. Esta versão foi então validada em indivíduos de idade entre 55 e 80 anos, com menos de cinco anos de escolaridade, recrutados em um hospital de Bangkok, Tailândia.…”

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Prevalência de transtornos mentais em idosos e comparação de instrumentos breves para rastreamento de transtorno neurocognitivo na atenção básica

Leal¹

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À toda minha família, em especial aos meus pais, José Libório e Maria de Lourdes, e minhas irmãs, Larissa e Letícia, que mesmo distantes fisicamente, sempre se fizeram presentes através do amor e apoio. A Francisco, pela companhia, cuidado e por me inspirar a ser uma pessoa melhor. Ao meu querido orientador, Prof. Dr. Marcos Hortes Nisihara Chagas, por ser inspiração, por toda paciência e acolhimento, pelas suas orientações valiosas e por ser luz e caminho para essa jornada. Aos idosos participantes, que disponibilizaram tempo e atenção se voluntariando tão generosamente a essa pesquisa, por darem sentido a tudo isso. Ao grupo ProVive, pela oportunidade de ingressar na pesquisa e pela ajuda na coleta dos dados. Às colegas de trabalho, Rebeca Mendes e Natália Mota Chagas, pela parceria na coleta e pelo compartilhamento de experiências diárias, o que deixou tudo mais leve e alegre. A Mirella Losapio pela companhia e parceria. Aos colegas médicos assistentes do HC-FMRP-USP pelo apoio. A Rosana Shuhama pela prontidão na ajuda e explicações valiosas sobre testes estatísticos. Aos meus amigos queridos e em especial os de residência, Alyssa Figueiredo, Luana Harada e Renato Silva, que estiveram presentes desde o início da jornada que me trouxe até aqui. À secretária do PGSM, Ivana, pelo auxílio e presteza nesses anos. À CAPES, por fomentar e proporcionar estrutura para o desenvolvimento de pesquisa e ciência no nosso país.

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Evaluation of Montreal cognitive assessment for the differential diagnosis of mild cognitive impairment and Alzheimer’s disease in elderly patients with more than 5 years of schooling: Data from a Brazilian sample

Cited by 8 publications

References 23 publications

Distinguishing mild cognitive impairment from healthy aging and Alzheimer’s Disease: The contribution of the INECO Frontal Screening (IFS)

Distinguishing mild cognitive impairment from healthy aging and Alzheimer’s Disease: The contribution of the INECO Frontal Screening (IFS)

Investigation of Play Intervention for Dementia (PID) Activities in Addressing Cognitive Domains Reflected in Hong Kong Montreal Cognitive Assessment (HK-MoCA)

Prevalência de transtornos mentais em idosos e comparação de instrumentos breves para rastreamento de transtorno neurocognitivo na atenção básica

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