Evaluation of Morning Glory Syndrome with Spectral Optical Coherence Tomography and Echography

Retinal detachment associated with optic disc colobomas and morning glory syndrome

“…Retinal detachment may develop in up to one-third of patients with morning glory syndrome and spontaneous resolution has also been observed. 12 Various theories have been advanced regarding the origin of the subretinal fluid seen in these eyesF cerebrospinal fluid, [1][2][3] or fluid from the vitreous space. [4][5][6][7][8][9][10][11] This issue remains a subject of controversy.…”

“…The two possible sources are the cerebrospinal fluid [1][2][3] or the vitreous cavity, [4][5][6][7][8][9][10][11] and tractional forces may have a role. 2,3,5,6 It also remains uncertain which treatment for these patients produce the best outcomes, as spontaneous resolution of retinal detachments may sometimes occur. Based on a study of a small number of eyes with peripapillary retinal detachment associated with optic disc coloboma or morning glory syndrome with optical coherence tomography (OCT), we believe that the mechanism causing retinal detachment in these eyes is similar.…”

Congenital Optic Nerve Malformations

“…Most patients have visual field defects. 36 Other ocular findings include microphthalmia (40%), 37 cataract, 39 abnormal arteriovenous and arterial-arterial anastamoses, 40 persistent fetal vasculature, 37,39 scleral or optic nerve calcification, 37 contralateral optic nerve pit, 41 amblyopia, 37 and nystagmus. Recent OCT studies in children and adults with MGDA have shown increased retinal nerve fiber layer thickening in the affected eye, with the temporal nerve fiber layer being the thickest.…”

Enhanced depth imaging optical coherence tomography of congenital cavitary optic disc anomaly (CODA)

“…Previous studies using swept-source and enhanced depth imaging (EDI)-OCT have described the appearance of optic disc colobomas, optic pits and morning glory syndromes. Herniation of dysplastic retina, abnormal communication between subarachnoidal- and subretinal spaces as well as detection of lamina cribrosa torn off of peripapillary sclera at the site of the excavation have been reported 8 10 11. These previous studies did not note unusual retinal pigment epithelium (RPE) configurations.…”

“…Morning glory optic disc anomalies have a deeply excavated optic disc and cilioretinal vessels which radiate from the disk's edge. It is a congenital funnel-shaped excavation of the posterior fundus that incorporates the optic disc 2 4 9 10. Previous studies using swept-source and enhanced depth imaging (EDI)-OCT have described the appearance of optic disc colobomas, optic pits and morning glory syndromes.…”