Evaluation of myocardial alterations using the enzymatic profile of elderly long-distance runners

Abstract

Elderly population often is encouraged to practice sports in preventing cardiovascular diseases. However, evidences exist that intense physical efforts are related with a higher risk for acute myocardial infarction and sudden death. Biological markers for myocardial injury was analyzed in a group of 15 elderly athletes without a history of coronary artery disease, who participated in the 77th International Sao Silvestre race (15,000 m) in Sao Paulo City. A statistical difference was observed between total CPK activity levels before the run, immediately after the run, and some time later. Similar results were observed in the concentration of CK-MB mass. The cardiac troponin I (TnI-c) levels remained unchanged and within normal limits during the same time periods. The results of the present study showed no evidence of myocardial injury in elderly subjects without a history of coronary artery disease after participating in long-distance runs, as confirmed by the analysis of TnI-c levels. The increase in total CPK activity levels and the concentration of CK-MB mass do not represent myocardial injury in these subjects.

Evaluating the Impact of Omega-3 Supplementation intake on Creatine Kinase index after one Session of Resistance Training in Inactive Individuals

“…Considering the role of enzymes and the effect of physical activity and the various consumables on them, the use of enzyme activity changes is very important in evaluation and diagnosis of diseases and tissue damage [15,16]. CK enzyme is one of the most well-known and most reliable clinical indicators, which is believed to increase the amount of the enzyme in the blood as damage to the heart-muscle cells in the body [16,17].In fact, unsaturated omega-3 fatty acids that are essential for the health of the body cannot be synthesized by body; therefore, they should be obtained through food or dietary supplements, the best source of which is fish, which contains more levels and groups of fatty acids [18].…”