Evaluation of Oral Hygiene Status, Salivary Fluoride Concentration and Microbial Level in Thalassemic and Hemophilic Patients

Nayak, Suryasnata; Govind, Shashirekha; Jena, Amit; Samal, Priyanka; Sahoo, Naresh Kumar; Rath, Shakti

doi:10.33192/smj.2022.38

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…According to studies, hemophilic patients are more resistant to dental visits and fear dentists [29]. Patients fear that dental procedures will cause bleeding episodes that can only be controlled by factor infusions, resulting in both physical and financial challenges [29,30]. For the treatment of symptomatic irreversible pulpitis, there is typically no contraindication for endodontic treatment in hemophiliac patients/thalassemic patients.…”

Section: Discussionmentioning

confidence: 99%

Local Anesthesia Onset and Pain Perception in Hemophilic and Thalassemic Conditions

Das

Govind

Jena

et al. 2023

JCM

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The study aims to evaluate and compare the onset of local anesthesia (LA) and pain perception during endodontic treatment in hemophilic and thalassemic patients. Methods: The study included 90 patients with symptomatic irreversible pulpitis of the mandibular molars. Three groups (n = 30 in each group) were included. Group 1: hemophilic patients; group 2: thalassemic patients; and group 3: individuals without any systemic diseases. Onset of LA and visual analogue scale (VAS) scores was recorded immediately after the administration of local anesthesia, during the pulp exposure procedure, and during canal instrumentation, and were compared between the three groups. Frequency distribution, ANOVA, and linear regression analysis (p < 0.05) were applied. Results: The mean onset time was 46 ± 34 s in the hemophilic group, 42 ± 23 s in the thalassemic group, and 38 ± 12 s in controls, but the differences were statistically insignificant. After LA administration (LA-VAS), all three groups experienced a statistically significant reduction in pain (p = 0.048). On pulp exposure (PE-VAS) (p = 0.82) and during canal instrumentation (CI-VAS) (p = 0.55), there was no statistically significant difference in pain perception between the groups. The coefficients indicate a positive correlation between the VAS and onset time, indicating a positive reduction in the VAS following the administration of LA. Conclusions: Hemophilic patients exhibited a clinically longer average onset time for LA. However, the difference among the three groups with regard to the overall pain perception after LA administration, during and after pulp exposure, and during canal instrumentation was statistically insignificant.

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Section: Discussionmentioning

confidence: 99%

Local Anesthesia Onset and Pain Perception in Hemophilic and Thalassemic Conditions

Das

Govind

Jena

et al. 2023

JCM

Self Cite

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Salivary dynamics: Assessing pH, glucose levels, and oral microflora in diabetic and non-diabetic individual

Mohanty,

Saha,

Mohanty

et al. 2024

IJMMTD

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: Diabetes significantly impacts oral health, including alterations in the oral microflora. Increased glucose levels in the oral cavity create an environment conducive to the growth of certain pathogenic bacteria, leading to various oral and systemic diseases. These organisms can then move to the bloodstream, causing systemic inflammation and leading to health problems like cardiovascular disease and systemic infections. : This study aimed to compare the salivary pH, glucose concentration, and oral microflora in diabetics and non-diabetics and to correlate that elevated salivary glucose can lead to oral and systemic infections. This single-centre, cross-sectional study involved 25 diabetics and 25 non-diabetics aged 18 years and above. The study duration was 60 days. Saliva samples collected from patients of both groups were subjected to biochemical and microbial analysis. In biochemical analysis, the pH and glucose concentrations were monitored. In microbial analysis, routine and PCR-based assays were used to identify the significant organisms from the saliva samples from both groups. : The average pH (7.028) of the non-diabetic individuals was higher, towards the neutral range; however, in diabetic individuals, the range (6.016) was towards acidic. The salivary glucose estimation results showed that the average glucose concentration in the non-diabetic group was less than in the diabetic group. The oral microbiological profile of diabetic patients differed from those of non-diabetics, where the number of bacterial colonies was significantly higher in diabetic individuals. Notably, the number of dental caries-causing bacteria was 25 in diabetic and 23 in nondiabetic patients. This can be attributed to the reduced pH of the saliva and the elevated glucose level. : The oral microbiological profile of diabetic patients differed from that of non-diabetics, with diabetics having considerably more bacterial colonies. Results suggested that diabetic individuals are at a higher risk of oral and systemic infections. Hence, maintaining balanced glucose levels can help protect oral health by limiting the nutrients available for pathogenic bacteria, reducing inflammation, and supporting immune function.

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Evaluation of Oral Hygiene Status, Salivary Fluoride Concentration and Microbial Level in Thalassemic and Hemophilic Patients

Cited by 2 publications

References 26 publications

Local Anesthesia Onset and Pain Perception in Hemophilic and Thalassemic Conditions

Local Anesthesia Onset and Pain Perception in Hemophilic and Thalassemic Conditions

Salivary dynamics: Assessing pH, glucose levels, and oral microflora in diabetic and non-diabetic individual

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