Evaluation of oral hygiene status and periodontal health in Down′s syndrome subjects in comparison with normal healthy individuals

Krishnan, CS; Kumari, Burnice Nalina; Sivakumar, G; Iyer, Srinivas Prasad; Ganesh, PR

doi:10.4103/2229-3019.148237

Cited by 5 publications

(5 citation statements)

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“…The influence of this finding in the overall results deserve a careful analysis and the influence of a poor plaque control in the onset of gingivitis and periodontitis should be considered. In light of the possible impact of the limited skills in supragingival biofilm control in DS individuals, this factor should be taken into consideration [11].…”

Section: Discussionmentioning

confidence: 99%

“…Early onset forms of periodontitis and late onset of caries lesions represent the most frequent oral conditions associated with DS subjects [9], which may become further aggravated by their motor disability and manual dexterity compromise, that limits their performance in oral hygiene practices [11]. Several observational studies have reported high prevalence of gingivitis and periodontitis (ranging from 58-96%) at young ages (less than 35) in DS subjects [12].…”

Section: Introductionmentioning

confidence: 99%

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Periodontal Condition and Subgingival Microbiota Characterization in Subjects with Down Syndrome

et al. 2021

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The aim was to study the subgingival microbiota in subjects with Down syndrome (DS) with different periodontal health status, using cultural and molecular microbiological methods. In this cross-sectional study, DS subjects were selected among those attending educational or occupational therapy centers in Galicia (Spain). Medical histories, intraoral and periodontal examinations and microbiological sampling were performed. Samples were processed by means of culture and quantitative polymerase chain reaction (qPCR). Microbiological data were compared, by one-way ANOVA or Kruskal-Wallis and chi-square or Fisher tests, according to their periodontal status. 124 subjects were included, 62 with a healthy periodontium, 34 with gingivitis and 28 with periodontitis. Patients with periodontitis were older (p < 0.01) and showed lower prevalence of hypothyroidism and levothyroxine intake (p = 0.01), presented significantly deeper pockets and more attachment loss (p ≤ 0.01). Both gingivitis and periodontitis subjects showed higher levels of bleeding and dental plaque. PCR counts of T. forsythia and culture counts of E. corrodens and total anaerobic counts were significantly higher in periodontitis patients. Relevant differences were observed in the subgingival microbiota of DS patients with periodontitis, showing higher levels of anaerobic bacteria, T. forsythia and E. corrodens, when compared with periodontally healthy and gingivitis subjects. Moreover, periodontitis subjects were older, had lower frequency of hypothyroidism and higher levels of dental plaque.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Periodontal Condition and Subgingival Microbiota Characterization in Subjects with Down Syndrome

et al. 2021

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“…These findings are in disagreement with many previous studies which reported poorer status of oral hygiene and higher prevalence of periodontal diseases in DS children than their normal population. 8,10,30,31 The reasons for this may include the reduced manual dexterity of the participants, joint laxity, and lack of comprehension of oral hygiene needs due to mental difficulties. They, therefore, need help to carry out routine oral hygiene measures.…”

Section: Discussionmentioning

confidence: 99%

“…The sample size of 119 participants was obtained by using open epi online sample size calculator. The statistics considered for sample size estimation was good oral hygiene status as 50% 10 , margin of error as 9% and 95% confidence level. The non-probability purposive sampling technique was employed.…”

Section: Methodsmentioning

confidence: 99%

Oral Health of Individuals with Down Syndrome in Karachi, Pakistan

Azfar¹,

Khan²,

Iqbal³

et al. 2018

J Pak Dent Assoc

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OBJECTIVE: To determine the frequency of dental caries and oral hygiene status of children with Down syndrome, Karachi, Pakistan. METHODOLOGY: It was a cross-sectional study conducted at Special needs children School Karachi, Pakistan & the duration of study was 6 months. Total 119 children with Down syndrome of age 5-20 years of either gender were enrolled. After taking informed consent the subjects were examined for dental caries and dental status. Dental caries were assessed by using DMFT index and Oral hygiene status was assessed by using oral hygiene index?simplified (OHI-S). The data was analyzed by using SPSS version 23. Results: The overall caries prevalence in the study population was 68.1% with an overall mean DMFT score of 1.10±1.31. Out of 119 children with Down syndrome, majority had good hygiene status (51.2%), 27.7% had fair hygiene status and 21% had poor hygiene status with overall mean OHI-S score of 1.79±1.43. CONCLUSION: A high prevalence of dental caries was observed among children with Down Syndrome. There is a high need for an epidemiological survey followed by the comprehensive dental care programs for these children, as well as efforts should be taken to encourage and promote parents of these children to improve their oral health.

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“…Oral mucosal cells have been cultured on either a natural [58] or synthetic [59] substrate and transplanted onto the eye. These cells are similar to limbal epithelial cells, they are stratified squamous non-keratinised cells which express CK3, P63 and ABCG2, as in corneal / limbal epithelial cells but not CK12 [60]. Clinical studies have shown that even though the oral mucosal cells improve visual acuity, there have been reports of neovascularisation at the peripheral region of the cornea [59].…”

Section: Transplantation Of Different Cell Typesmentioning

confidence: 99%