2020
DOI: 10.1111/dth.14640
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Evaluation of oral isotretinoin effects on hearing system in patients with acne vulgaris: Reversible or not?

Abstract: Systemic isotretinoin is commonly used for severe acne treatment. It has many side effects, one of these is about hearing system, which has rarely been reported, also previous studies reported contradictory results about systemic isotretinoin and its association with hearing system. In this study, we aimed to investigate whether systemic isotretinoin affected on the hearing system or not. The study included 32 acne vulgaris patients (64 ears) who treated with oral isotretinoin 0.5 mg/kg body weight for at leas… Show more

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Cited by 2 publications
(1 citation statement)
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“…Last year, Kemeriz et al stated a hypothesis that reversible hearing loss during an oral isotretinoin course might be caused by hyperlipidemia, which leads to a decrease in cochlear oxygenation, direct toxicity on the cochlea, or a decrease in vascularization. Thus, research in this area should be extended [ 51 ].…”
Section: Discussionmentioning
confidence: 99%
“…Last year, Kemeriz et al stated a hypothesis that reversible hearing loss during an oral isotretinoin course might be caused by hyperlipidemia, which leads to a decrease in cochlear oxygenation, direct toxicity on the cochlea, or a decrease in vascularization. Thus, research in this area should be extended [ 51 ].…”
Section: Discussionmentioning
confidence: 99%