2020
DOI: 10.14260/jemds/2020/93
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Evaluation of Oral Microbial Flora in Saliva of Patients of Oral Submucous Fibrosis

Abstract: BACKGROUND Oral Submucous Fibrosis (OSMF) has a multifactorial origin and the risk factors vary across different parts of the world. Betel nut (areca nut) chewing is the leading cause of OSMF in parts of South East Asia as well as Indian subcontinent. Certain fungal species have been identified in the occurrence of various premalignant lesions including OSMF. Candida in mouth along with the epithelial changes like atrophy, dysplasia, and hypertrophy may predispose individuals to premalignancy. This study was c… Show more

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Cited by 5 publications
(4 citation statements)
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“…He eventually developed septic shock and acute renal failure. The patient succumbed on day 14 of hospitalization [17].…”
Section: Discussionmentioning
confidence: 99%
“…He eventually developed septic shock and acute renal failure. The patient succumbed on day 14 of hospitalization [17].…”
Section: Discussionmentioning
confidence: 99%
“…It was concluded that the development and progression of oral squamous cell carcinoma leads to changes in the pattern, composition and behavior of certain specific gram negative and gram positive bacterial groups and that these changes are in conjunction to each other. A number of studies reflected on different aspects of oral squamous cell carcinoma [6][7][8][9][10][11][12][13][14][15][16][17][18].…”
Section: Discussionmentioning
confidence: 99%
“…For example ciprofloxacin to Pseudomonas aeruginosa biofilms [8] cetrimide vulnerability is reduced in E. coli [15]. The factors which contribute to the resistance which is shown by bacteria due to biofilm formation includes inability of antimicrobials to penetrate biofilms, limitations of nutrients, and deposition of toxic metabolites and lower oxygen tension [23][24][25].…”
Section: Treating Biofilm Infectionmentioning
confidence: 99%