Evaluation of Pain Following the Use of Different Single-file Glide Path Systems: A Randomized Clinical Trial

Danaci, Zeliha; Yeter, Kübra Yeşildal

doi:10.1016/j.joen.2023.10.017

Journal of Endodontics

2024

DOI: 10.1016/j.joen.2023.10.017

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Evaluation of Pain Following the Use of Different Single-file Glide Path Systems: A Randomized Clinical Trial

Zeliha Danaci,

Kübra Yeşildal Yeter

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2024

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Cited by 3 publications

References 41 publications

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Aminoshariae,

Azarpazhooh,

Fouad

et al. 2024

Journal of Endodontics

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Insights into the February 2024 Issue of the Journal of Endodontics

Aminoshariae,

Azarpazhooh,

Fouad

et al. 2024

Journal of Endodontics

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Adherence to Registration and Selective Outcome Reporting in Randomized Clinical Trials Published in Endodontic Journals Over the Past 5 Years: A Meta-Research Study

Vitali,

Santos,

Rocha

et al. 2024

Journal of Endodontics

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Effect of sublingual fast-dissolving piroxicam premedication on postoperative pain experience in mandibular molars with non-vital pulp: a randomized double-blind controlled trial

Mohamed,

El-Asfouri,

Amin

2024

Head Face Med

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Background The aim of this trial was to evaluate the effect of a preoperative, single dose sublingual fast-dissolving piroxicam (20 mg) compared to placebo on postoperative pain at rest (POP), on biting (POPB) and on percussion (POPer) after single-visit endodontic treatment of asymptomatic mandibular molars with non-vital pulp. Methods Seventy patients randomly received either piroxicam or placebo 1 h before treatment (n = 35). Patients recorded their pain (POP and POPB) level 6 h, 12 h, 24 h, 48 h, 72 h and 7 days postoperatively using an 11-point numerical rating scale; POPer was assessed after 7 days. Resuce-analgesic intake (RAI) and flare-up incidence (FUI) were recorded. Data were statistically analyzed. Results Both groups had similar baseline characteristics (P > 0.05). Piroxicam showed less POP intensity and incidence than placebo at 6, 12 and 24 h, less POPB intensity and incidence at all timepoints, less POPer intensity and incidence and less RAI (p > 0.05), but similar FUI (P > 0.05). A significant rise in pain compared to baseline occurred with placebo from 6 to 72 h for POP and to 7 days with POPB (p > 0.05); such rise was not detected with piroxicam. POPB showed higher pain intensity than POP at all time points (p < 0.05). No swelling or adverse effects occured. Conclusions A preoperative single dose of sublingual fast-dissolving piroxicam can be effective in reducing spontaneous pain up to 24 h, stimulated pain up to 7 days, and RAI incidence in asymptomatic mandibular molars with non-vital pulp; it can prevent rise in POP and POPB postoperatively. Stimulated postoperative pain can be more severe and longer lasting than spontaneous pain. Trial registration Clinicaltrials.gov ID: NCT03998826 (2019).

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Evaluation of Pain Following the Use of Different Single-file Glide Path Systems: A Randomized Clinical Trial

Cited by 3 publications

References 41 publications

Insights into the February 2024 Issue of the Journal of Endodontics

Insights into the February 2024 Issue of the Journal of Endodontics

Adherence to Registration and Selective Outcome Reporting in Randomized Clinical Trials Published in Endodontic Journals Over the Past 5 Years: A Meta-Research Study

Effect of sublingual fast-dissolving piroxicam premedication on postoperative pain experience in mandibular molars with non-vital pulp: a randomized double-blind controlled trial

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