Evaluation of Pain Levels After Nd: YAG Laser and Scalpel Incisions: An Experimental Study In Rats

Kara, Cankat; Süleyman, Halis; Tezel, Ayfer; Orbak, Recep; Çadırcı, Elif; Polat, Beyzagül; Kara, İsmail Hamdi

doi:10.1089/pho.2009.2639

Cited by 12 publications

(14 citation statements)

References 19 publications

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“…The postoperative pain model in rats was established using a well-known conventional technique [5]. With the exception of the healthy (HG) group, the upper part of the hind foot of all rats was cut lengthwise with a surgical scalpel.…”

Section: Effects Of Metamizole and Paracetamol On Pain In The Rat Pawmentioning

confidence: 99%

“…The role of cyclo-oxygenase-2 (COX-2) and polymorphonuclear leukocytes (PNLs) in the postoperative pain mechanism has been demonstrated in literature [3,4]. The postoperative pain models employed in the present study are the pain originating from surgical trauma [5] and the carrageenan pain model. These pain models were established through a scalpel lesion or injection of carrageenan to the rat paw.…”

Section: Introductionmentioning

confidence: 97%

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A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats

İnce

Aksoy

Ahıskalıoğlu

et al. 2015

Journal of Investigative Surgery

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Section: Effects Of Metamizole and Paracetamol On Pain In The Rat Pawmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats

İnce

Aksoy

Ahıskalıoğlu

et al. 2015

Journal of Investigative Surgery

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“…Also, the Nd:YAG laser offers some benefits in the surgical field. The wavelengths of this laser are absorbed by pigmented tissues, making it very effective for surgical cutting and coagulating dental soft tissue with good homeostasis 6‐10 . Consequently, the Nd:YAG laser has been described for use in oral soft tissue management 10 …”

Section: Discussionmentioning

confidence: 99%

“…Historically, the public has associated dental treatment with pain, so pain control is very important for the physical and dental wellbeing of the patient and for the effectiveness of therapy. However, to the best of the authors’ knowledge, there are few studies that investigate the postoperative effects of laser treatment, 3,7‐9 but reduced postoperative pain from oral surgical procedures has been claimed after laser tissue ablation 9 …”

Section: Discussionmentioning

confidence: 99%

“…Various treatment methods for oral soft tissue lesions have been used: 1) conventional surgery; 2) cryosurgery; 3) electrodessication; 4) intralesional administration of corticosteroids or sodium tetradecyl; 5) radiotherapy; 6) embolization with steel coil, gel foam, silicone beads, or cyanoacrylate; and 7) laser therapy (especially the neodymium:yttrium‐aluminum‐garnet [Nd:YAG] laser) 4,5 . In dentistry, the Nd:YAG laser has been commonly used for soft tissue surgery, and its advantages over conventional surgeries, including increased coagulation, ablation or vaporization, hemostasis, sterilization, and decreased swelling, edema, and pain, have been accepted by various authors 6‐9 . In those studies, advantages were usually determined using patient responses and clinical findings.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of Different Oral Soft Tissue Lesions With Surgical Neodymium: Yttrium‐Aluminum‐Garnet Laser: Case Series

Gökmenoğlu

Sadik

Yavuz

et al. 2016

Clin Adv Periodontics

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Introduction: Oral soft tissue lesions cause discomfort and potentially serious clinical problems. Case Series: These case reports present different gingival and/or mucosal lesions (pyogenic granuloma, verruca vulgaris, giant cell granuloma, fibroma, etc.) and the surgical treatment of these lesions with a neodymium:yttrium‐aluminum‐garnet (Nd:YAG) laser (320‐μm optic fiber; 4 W; 100 mJ, 40 Hz; emission mode, pulsed, and contact mode). Patients were evaluated after laser surgery on degree of postoperative pain; discomfort; functional complications (eating and speech); and recurrence. Results indicated that patients had minimal postoperative pain, few functional complications, and low rates of pain. Laser surgery produced minimal bleeding, damage to the surrounding tissue, and post‐surgical edema. Conclusion: In these cases, the Nd:YAG laser provided a non‐bleeding environment at the surgical area with an acceptable operating time, quick postoperative hemostasis, good patient acceptance, low rates of pain, and no post‐treatment adverse events among patients with oral soft tissue lesions.

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Investigation of mucus obtained from different fish species on the acute pain induced with scalpel incision in paw of rats

et al. 2016

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No comparative study could be found for the analgesic activity of mucuses from the Oncorhynchus mykiss (OM), Salvelinus fontinalis (SF), Salmo coruhensis (SC), Acipenser gueldenstaedtii (AG), and Acipenser baerii (AB) fish species in the literature. We aimed to investigate the effects of mucuses obtained from the abovementioned fish species on scalpel incision-induced pain in the rat paw and to examine the role of oxidant/antioxidant parameters and COX-2 gene expression in the analgesic activities. Animals were divided into groups: SIC (scalpel incision; SI), SIDS (SI+25 mg/kg diclofenac sodium), SOM (SI+25 mg/kg OM mucus), SFM (SI+25 mg/kg SF mucus), SCM (SI+25 mg/kg SC mucus), SAgM (SI+25 mg/kg AG mucus), SAbM (SI+25 mg/kg AB mucus), and HG (healthy). The paw pain thresholds were measured with a Basile algesimeter before and after diclofenac sodium (DS) or mucus administration, and then the rats were euthanized with thiopental sodium. Oxidant/antioxidant and COX-2 gene expression parameters were measured in paw tissues. OM, SC, AG, and AB fish mucuses could not decrease the SI-induced pain. However, SF fish mucus prevented this pain by 69% after the first hour and by 58.3% after the third hour. DS was shown to suppress pain more weakly than SF, preventing the pain by 62.1% and 50.0% after the first and third hours, respectively. SF mucus and DS significantly inhibited increase of COX-2 gene expression, while other fish mucuses could not. None of the fish mucuses except SF mucus in conjunction with DS could significantly inhibit the increase in oxidant parameters and decrease in antioxidants. SF fish mucus should be comparatively assessed in clinical practice for treatment of postoperative pain.

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Evaluation of Pain Levels After Nd: YAG Laser and Scalpel Incisions: An Experimental Study In Rats

Abstract: The results suggested that, for soft tissue surgery, Nd: YAG lasers have often led to shorter operative times, less pain, and fewer postoperative adverse events.

Cited by 12 publications

References 19 publications

A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats

A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats

Treatment of Different Oral Soft Tissue Lesions With Surgical Neodymium: Yttrium‐Aluminum‐Garnet Laser: Case Series

Investigation of mucus obtained from different fish species on the acute pain induced with scalpel incision in paw of rats

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