Evaluation of Patient Age as a Risk Factor for Intraocular Pressure Elevation After Intravitreal Triamcinolone

Intraocular pressure elevation following triamcinolone acetonide administration as related to administration routes

“…Previous reports have confi rmed the following risk factors for TA-induced IOP elevation: younger age, [17][18][19][20][21][22] uveitis, 14,23 higher baseline IOP, 13,21,24 IV injection 18,21 and diabetes mellitus. 25 In the present study, younger age, higher baseline IOP, and simultaneous sub-Tenon capsule injection and intravitreal injection were risk factors for IOP elevation.…”

Risk factors for steroid response among cataract patients

“…5 The overall study population had a similar mean age (71.5 G 11.8 years) to ours, and there was a 16% reduction in risk associated with a 10-year increase in age. In a smaller study, Shukla et al 9 evaluated steroid response (defined as IOP O21 mm Hg) in 164 eyes injected with intravitreal triamcinolone acetonide. Fourteen (45%) of 31 patients younger than 45 years had an IOP rise compared with 28 (21%) of 133 patients older than 45 years (PZ.006).…”

Loteprednol Etabonate 0.5%/Tobramycin 0.3% Compared with Dexamethasone 0.1%/Tobramycin 0.3% for the Treatment of Blepharitis

“…24 Further research into this phenomenon is warranted to confirm if there is a higher predisposition to steroid-induced IOP elevation in patients of Asian ethnicity. It is also worth noting that the average age of the China study population was about 14 years younger than that of the US study population, and younger age has also been associated with steroid-induced IOP elevations.- 20,25 Furthermore, different techniques were used to measure IOP in the US (applanation tonometry) and China (non-contact tonometry) studies. Non-contact tonometry has been shown to overestimate IOP relative to applanation tonometry in some studies, 26,27 while others have reported similar results between the two methods.…”