Evaluation of patients’ radiation doses and establishment of institutional diagnostic reference levels in nuclear medicine in Oman

Abstract

This study aimed to develop diagnostic reference levels (DRLs) in Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) and Positron Emission Tomography/Computed Tomography (PET/CT) imaging for the most frequent SPECT/CT and PET/CT examinations performed at our institution. A total of 1134 adult patients, who have undergone SPECT/CT and PET/CT scanning over a period of 4 years (2018–2021), were included. The scans consisted of 401 PET/CT and 733 SPECT/CT scans. The CT dosimetry data [CT-dose-index (CTDIvol), dose-length-product (DLP)] and administered activities were collected. The DRLs were calculated for CTDIvol, DLP and administrated activity. The estimated DRLs are given as [median CTDIvol (mGy):median DLP (mGy.cm):median administrated activity (MBq)]: whole body PET/CT: 1.88:175:259; brain PET/CT: 12.9:300:239; cardiac PET/CT: 1.34:32:368; bone SPECT/CT: 2.68:116:763; MPI SPECT/CT (stress-rest): 1.49:52:751-721; parathyroid SPECT/CT: 3.1:126:779; thyroid uptake SPECT: 3.52:147:195; thyroid post-ablation SPECT/CT: 3.85:160:NA. The derived DRLs have allowed careful monitoring of doses delivered to patients and could act as a trigger to investigate doses that systematically exceeds the derived DRLs.