Evaluation of pharyngo‐oesophageal involvement in pemphigus vulgaris and its correlation with disease activity

Okamura, Akihiko; Nakamura, Rieko; Yamagami, Jun; Ishii, Ken; Kawakubo, Hirofumi; Omori, Tai; Takeuchi, Hiroki; Amagai, Masayuki; Kitagawa, Yuukou

doi:10.1111/bjd.14725

Cited by 6 publications

(4 citation statements)

References 15 publications

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“…4 In fact, esophageal involvement has a relatively high incidence ranging from 46 to 87%, but EGD was done infrequently enough to detect. 5 Esophageal involvement in pemphigus vulgaris usually presents with throat pain, dysphagia, odynophagia or even bleeding. However, patient with oropharyngeal and upper esophageal involvement presented with an epigastric pain is very uncommon.…”

Section: Discussionmentioning

confidence: 99%

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Pemphigus vulgaris presenting with epigastric pain

Elmassry

Thongpiya

Yingchoncharoen

et al. 2023

Clinical Case Reports

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Key Clinical Message Pemphigus vulgaris is an autoimmune mucocutaneous disease with an involvement in gastrointestinal tract especially in oral cavity and esophagus. Ulcers can be the initial presentation even before visible mucosal or cutaneous lesions. The presenting symptoms will be in accordance with the affected organ such as throat pain, hoarseness, dysphagia, odynophagia, or even bleeding. Here, we report a case of undiagnosed pemphigus vulgaris presenting with epigastric pain whose endoscopy showed oropharyngeal involvement and isolate esophageal ulcer, which failed proton pump inhibitor treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

“…White patches of hyperkeratosis can be seen after PV heals 4 . In fact, esophageal involvement has a relatively high incidence ranging from 46 to 87%, but EGD was done infrequently enough to detect 5 . Esophageal involvement in pemphigus vulgaris usually presents with throat pain, dysphagia, odynophagia or even bleeding.…”

Section: Discussionmentioning

confidence: 99%

Pemphigus vulgaris presenting with epigastric pain

Elmassry

Thongpiya

Yingchoncharoen

et al. 2023

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…4 In fact, esophageal involvement has a relatively high incidence ranging from 46-87%, but EGD was done infrequently enough to detect. 5 Esophageal involvement in pemphigus vulgaris usually presents with throat pain, dysphagia, odynophagia or even bleeding. However, patient with oropharyngeal and upper esophageal involvement presented with an epigastric pain is very uncommon.…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Vulgaris Presenting with Epigastric Pain

Elmassry

Thongpiya

Yingchoncharoen

et al. 2023

Preprint

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Pemphigus vulgaris is an autoimmune mucocutaneous disease with an involvement in gastrointestinal tract especially in oral cavity and esophagus. Ulcers can be the initial presentation even before visible mucosal or cutaneous lesions. The presenting symptoms will be in accordance with the affected organ such as throat pain, hoarseness, dysphagia, odynophagia or even bleeding. Here, we report a case of undiagnosed pemphigus vulgaris presenting with epigastric pain whose endoscopy showed oropharyngeal involvement and isolate esophageal ulcer, which failed proton pump inhibitor treatment.

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“…1 Recent studies have shown a relatively high incidence (46-87%) of esophageal involvement in PV that is often associated with a high fragility of the esophageal mucosa. 2 To our knowledge, here, we present the first case of endoluminal vacuum therapy (EVT) for a patient with esophageal involvement in PV and with associated iatrogenic perforation of the proximal esophagus.…”

Section: Introductionmentioning

confidence: 99%

Endoluminal Vacuum Therapy for Iatrogenic Perforation of the Proximal Esophagus—Case Report of a Patient with Esophageal Involvement in Pemphigus Vulgaris

Wächter

Schiffmann

Denzer

2020

Journal of Digestive Endoscopy

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Pemphigus vulgaris (PV) is a rare autoimmune disease affecting the skin and mucous membranes. Recent studies have shown a relatively high incidence of esophageal involvement in PV. To distinguish between the esophageal involvement of PV and other pathologies, early endoscopic evaluation is essential to obtain tissue for histological analysis. Here, we present the first case of endoluminal vacuum therapy (EVT) for a patient with esophageal involvement in PV and with associated iatrogenic perforation of the proximal esophagus. In comparison to classical treatment options for perforations of the proximal esophagus consisting of either stent insertion or surgical intervention, EVT seems to be a promising alternative with a good clinical outcome.

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Evaluation of pharyngo‐oesophageal involvement in pemphigus vulgaris and its correlation with disease activity

Cited by 6 publications

References 15 publications

Pemphigus vulgaris presenting with epigastric pain

Pemphigus vulgaris presenting with epigastric pain

Pemphigus Vulgaris Presenting with Epigastric Pain

Endoluminal Vacuum Therapy for Iatrogenic Perforation of the Proximal Esophagus—Case Report of a Patient with Esophageal Involvement in Pemphigus Vulgaris

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