Evaluation of Phytochemical, Chemical Composition, Antioxidant and Antimicrobial Screening Parameters of Rhamnus prinoides (Gesho) Available in the Market of Mekelle, Tigray, Ethiopia

Amabye, Teklit Gebregiorgis

doi:10.4172/2329-6836.1000198

Cited by 15 publications

(24 citation statements)

References 42 publications

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“…On the other hand, results of the current study were contrasted with that of [6] and [26] who reported aqueous extract of Rhamnus prinoides leaves was found to be devoid of antibacterial activities against all the test bacterial strains regardless of the concentrations. Another study conducted by [3] reported that, water extracts of Avicennia marina did not give any inhibition against Staphylococcus sp.…”

Section: Discussioncontrasting

confidence: 99%

“…Among extracts of the plant used in the study, the ethanol extract of Rhamnus prinoides fruits showed the maximum zone of inhibition which was in line with the study of [33] The current results were disagreed with that of [26] aureus were 400 mg/ml and 200 mg/ml respectively [6].…”

Section: Discussionsupporting

confidence: 76%

“…Results of the current study were also in line with the study of[26] who reported that methanol fraction of Rhamnus prinoides leaves showed the highest antibacterial activity against standard strains of S. aureus and the lowest antibacterial activity against clinical isolates of E. coli. According to the study conducted in Algeria, Punica granatum bark ethanol macerate showed to be potent inhibitors against all bacterial strains[20] and methanol water extract of Rhamnus prinoides leaves was active against all bacteria strains[6]. Lawsonia inermis showed the zone of inhibition 7.20 mm against E. coli in disc diffusion method[4] which were lower than the result of this study.…”

contrasting

confidence: 58%

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Antibacterial Activity of Rhamnus prinoides extracts against Staphylococcus aureus and Escherichia coli

Geta

Kibret

2019

Preprint

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Medicinal plants offer a major and accessible source of health care to people living in developing countries. Increasing in resistant microbial infections intensified the search for new, safer, and more efficacious agents to combat serious microbial infections. Acanthus sennii is one of the medicinal plants used traditionally for treatment of different infectious diseases in Ethiopian. Therefore, this research was carried out to evaluate antibacterial activity of Acanthus sennii against pathogenic bacteria. The antimicrobial activity tests of the plant extracts against pathogenic bacteria were carried out by the agar well diffusion method. Broth dilution and streak plate method were used to determine MIC and MBC of extracts respectively. The results revealed that ethanol extracts of leaves showed the highest antibacterial activity against standard strains of S.aureus with inhibition zone of 14±0.58mm and 17±0.67mm at 50mg/ml and at 25mg/ml respectively. Ethanol extracts of buds showed the highest antibacterial activity against standard strains of S.aureus with inhibition zone of 25.67±0.67mm at 100mg/ml. The lowest mean MIC value (2.6±0.52 mg/ml) was recorded with ethanol extract of leaves against standard strains and clinical isolates of S. aureus. The lowest mean MBC value (4.2±1.04 mg/ml) was recorded with ethanol extract of leaves against standard strains of S. aureu. Acanthus sennii could be a good candidate in the search for new antibacterial agents from natural products against bacterial pathogens. Therefore, further studies are needed to study their toxicology and isolate the bio- active components from this plant. Key words: Acanthus sennii, Antibacterial activity, MIC, MBC, pathogenic bacteria

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 76%

contrasting

confidence: 58%

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Antibacterial Activity of Rhamnus prinoides extracts against Staphylococcus aureus and Escherichia coli

Geta

Kibret

2019

Preprint

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“…Contains anthraquinones emodin, emodinanthrone, prinoidin and the flavonoid rhamnazin (Berhanu and Martin GP, 1995), tannins, alkaloids, cardiac glycosides, triterpene, saponins, phenols and resins; methanol water extract has antibacterial (Amabye, 2015) antimalarial activity (Muregi et al, 2007).…”

Section: Rhamnus Prinoides (Rhamnaceae)mentioning

confidence: 99%

Medicinal plants used in the management of diabetes by traditional healers of Narok County, Kenya

Kamau¹,

Mbaabu²,

Karuri³

et al. 2017

TANG [HUMANITAS MEDICINE]

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The Maasai community from Kenya is highly esteemed for their strong adherence to traditional cultures and ethno medicine. This is attributed to their age-old traditional mechanisms of passing down knowledge to the younger generation. Adoption to new socio-economic lifestyle and urbanization has been associated with development of diabetes, which has been reported among some indigenous pastoral communities in Kenya. Documentation of traditional methods of treatment and management of diabetes by the Maasai has not yet been reported, yet it is noteworthy. Thirty traditional healers from Narok County were purposively selected and interviewed about traditional knowledge of antidiabetic medicinal plants, parts used, preparation dosage and administration. A total of 14 antidiabetic plant species distributed within 13 genera and 12 families were identified and documented as herbal medicine used in the management of diabetes. The most highly cited plant species was Dovyalis abyssinica (20%), the plant family Flacourtiaceae and Rhamnaceae (2 plant species each) recorded the highest number of plant species while the most frequently used plant part was the roots (46%). Literature review revealed that some of the cited plants have known phytochemicals with antidiabetic activity; the study recommends further scientific investigation to validate their efficacy and safety.

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“…Datura stramonium, Gunnera perpensa, R. prinoides, Salix mucronata, S. nigrum, and Withania somnifera for their chemical properties. Presence of a wide array of chemical compounds has been reported in several plants (number shown in brackets) including alkaloids (15), anthraquinones (8), coumarins (2), flavonoids (19), glycosides (17), saponins (15), tannins (14), and terpenoids (11). Many of these compounds are known to have several pharmacological effects such as anti-allergic, antibacterial, antifungal, anti-inflammatory, anti-mutagenic, antiplasmodial, antioxidant, and anti-tumour, to name but a few.…”

Section: Phytochemical Datamentioning

confidence: 99%

A Review of Medicinal Plants Used by the Basotho for Treatment of Skin Disorders: Their Phytochemical, Antimicrobial, and Anti-Inflammatory Potential

Moteetee¹,

Kose²

2017

Afr J Tradit Complement Altern Med

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Background: While the incidence of skin diseases is high in developing countries, they are not regarded as priority due to low mortality rates, however, they are a major concern due to their co-occurrence with HIV/AIDS. Due to lack of accessibility to healthcare facilities and unaffordability of conventional medicines, many people in rural areas resort to medicinal plants. The aim of the study is to document the plants used for treating skin afflictions by the Basotho people residing in Lesotho and the Free State Province of South Africa. Materials and Methods: A comprehensive survey of existing ethnobotanical literature including numerous books was carried out. Electronic databases such as Google Scholar, PubMed, and ScienceDirect were also used to obtain information on the antiinflammatory, antimicrobial, and phytochemical activities of the medicinal plants. Results and discussion: 57 plant species are utilised for the treatment of various skin ailments with a majority of them used for wounds (26 species) and venereal sores (19 species). The plants are distributed in 39 families with the Asteraceae being the most represented with seven species, followed by Solanaceae and Asphodelaceae with four species each. 38 species have previously been evaluated for their phytochemical properties, 40 for their anti-microbial potential, while 29 have been assessed for their antiinflammatory activity. Of the 57, 13 species have not been evaluated for any of the three categories. Conclusion: Many of the plants have been shown to have anti-microbial, anti-inflammatory, and phytochemical properties, which then validates their traditional use.

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Evaluation of Phytochemical, Chemical Composition, Antioxidant and Antimicrobial Screening Parameters of Rhamnus prinoides (Gesho) Available in the Market of Mekelle, Tigray, Ethiopia

Cited by 15 publications

References 42 publications

Antibacterial Activity of Rhamnus prinoides extracts against Staphylococcus aureus and Escherichia coli

Antibacterial Activity of Rhamnus prinoides extracts against Staphylococcus aureus and Escherichia coli

Medicinal plants used in the management of diabetes by traditional healers of Narok County, Kenya

A Review of Medicinal Plants Used by the Basotho for Treatment of Skin Disorders: Their Phytochemical, Antimicrobial, and Anti-Inflammatory Potential

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