Acne scars are the most common sequelae of the severe inflammatory process of acne. They affect almost 95 percent of patients with acne vulgaris, which is prevalent in more than 90 percent of adolescents. 1,2 Scars are characterized by a loss or damage of tissue, vary in morphological characteristics such as shape, size, and depth, 3 and are graded as various types such as rolling, boxcar, and ice pick. Furthermore, they can be erythematous at the early stage, or may get purplish or pigmented as they develop. 4,5 In most patients, acne scars are mixed types and distributed around the face. A standard tool for assessing atrophic scars is the four-grade Goodman and Baron classification. 6 Managing acne scars is a challenge, 7-10 and therapies are divided into nonsurgical and surgical. The former includes anti-acne agents, 11,12 chemical peels, 13 microneedling, 14-17 and ablative 18 and nonablative fractional 19-22 and nonfractional 23 lasers, as well as autologous growth factors. 24-27 The latter include subcision, 28-30 autologous cell regeneration, 31 and autologous adipose-derived stem cells. 32