Evaluation of point‐of‐care International Normalized Ratio in sickle cell disease

Abstract

The reliability of point-of-care (POC) International Normalized Ratio (INR) may be affected by anemia.• The evidence on accuracy of POC-INR in sickle cell disease (SCD) is lacking.• Predictability of POC-INR in SCD is high except when POC-INR values are ≥4.• Applying a correction factor to POC-INR ≥4 in SCD improves accuracy.