“…Synthetic materials include poloxamers, 72,73 poly(N-isopropylacrylamides) 74,75 and polyethylene glycol. 76,77 Poloxamer is a synthetic amphiphilic copolymer 78,79 consisting of a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymer (Fig.…”