2024
DOI: 10.1097/scs.0000000000010827
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Evaluation of Postoperative Outcomes Following Early and Late Palate Repair: A Preclinical Study

Fabiana Aellos,
Ishita Verma,
Melody Ly
et al.

Abstract: Objective: To quantitatively assess the impact of early versus late surgical intervention on midfacial growth using a mouse model. Methods: A full-thickness mucoperiosteal flap surgery was performed on newborn (P17) mice and on neonatal (P30) mice. High-resolution micro–computed tomographic imaging coupled with histomorphometric analyses was used to assess craniomaxillofacial growth. Histology and immunohistochemical analyses were used to assess cellula… Show more

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