Evaluation of prefabricated adjustable thermoplastic mandibular advancement devices (PAT-MADs) for obstructive sleep apnea: an Asian experience

Soh, Leonard Jie Min; Han, Hongjun; Yu, Yue; Tay, Jin Yu; Ying, Hao; Toh, Song Tar

doi:10.1016/j.sleep.2020.02.025

Cited by 5 publications

(3 citation statements)

References 15 publications

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“…Low cost, comfort, ease of use, high tolerability, and relatively mild and transient side effects of MADs allow high levels of compliance [2]. myTAP ™ [13] and other trial devices [14,15] are effective in the treatment of obstructive sleep apnoea and represent an economical alternative to customized devices. ey are highly effective in selecting patients who are responders and candidates for therapy with personalized MAD.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of a Trial Oral Appliance in OSAS Management: A New Protocol to Recognize Responder/Nonresponder Patients

Segù

Santagostini

et al. 2021

International Journal of Dentistry

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Oral appliances (OAs) of various types have shown variable success in the treatment of mild-to-moderate obstructive sleep apnoea (OSA). In an OSA sample, this study evaluated the efficacy of a diagnostic trial OA (myTAP™); the efficacy of a definitive custom-fitted mandibular advancement device (MAD) (SomnoDent Flex™); and whether a trial device can be used to distinguish treatment responder from nonresponder patients. Patients underwent overnight home sleep recordings prior to and after fitting of these appliances in order to objectively assess their sleep quality in terms of polysomnographic (PSG) respiratory measures: apnoea-hypopnoea index (AHI), oxygen desaturation index (ODI), and minimum oxygen saturation (LowSpO2). 40 patients with symptomatic OSAS were enrolled, 33 males and 7 females, with a mean age of 55.6 ± 12.73 years and an initial (T0) AHI of 26.51 ± 14.79. Trial devices were used in 16 patients (AHI: 29.9 ± 19.97, ODI: 21.06 ± 16.05, and LowSpO2: 82 ± 10.22 at T0) and definitive MADs in 28 (AHI: 23.90 ± 9.19, ODI: 16.27 ± 11.34, and LowSpO2: 82.87 ± 6.04 at T0). Statistically significant decreases in AHI (9.59 ± 8.94, p < 0.0023 ) and ODI (8.20 ± 9.67, p < 0.0129 ) were observed after treatment with the trial device. Only 8 of the patients in the trial device group went on to use the definitive device. Treatment with the definitive MAD produced statistically significant decreases in AHI (11.46 ± 9.65, p < 0.0001 ) and ODI (9.10 ± 8.47, p < 0.0016 ) and a significant improvement in LowSpO2 (85.09 ± 6.86, p < 0.0004 ). Thus, both types of device proved effective in improving the PSG parameters. This study showed that introducing an easy-to-make and low-cost trial device into the therapeutic pathway of OSAS patients can circumvent the problem of individual responses to treatment by allowing effective classification of patients: in short, it allows a first distinction to be drawn between responders and nonresponders to treatment.

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Section: Discussionmentioning

confidence: 99%

Efficacy of a Trial Oral Appliance in OSAS Management: A New Protocol to Recognize Responder/Nonresponder Patients

Segù

Santagostini

et al. 2021

International Journal of Dentistry

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“…A different study examined the use of direct-to-consumer prefabricated adjustable thermoplastic mandibular advancement devices (PAT-MADs), its effectiveness in the treatment of OSA, feasibility, and short-term adherence in a Chinese population. 383 Fifty patients diagnosed with mild to moderate OSA on formal PSG were fitted with a PAT-MAD. Level 3 home sleep apnea testing (HSAT) was used at baseline and after treatment to measure sleep indices including AHI, hypopnea index (HI), apnea index (AI), oxygen desaturation index (ODI), and the lowest O 2 saturation (L sat ).…”

Section: Oral Appliance Therapymentioning

confidence: 99%

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

Cagna

Donovan

McKee³

et al. 2021

The Journal of Prosthetic Dentistry

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“…Additional research has focused on whether temporary appliances can play a role in helping to determine the therapeutic position of an appliance 9-12 and predicting which patients are likely to respond or not respond to OAT. [13][14][15][16][17][18] Dentists considering the use of a temporary appliance for a patient should be aware that these studies have limitations. None are long-term studies, and the literature yields few data about the use of temporary appliances selected and fit by patients themselves without the supervision of a qualified dentist per the American Academy of Dental Sleep Medicine (AADSM); 19 therefore, the conclusions that can be drawn from the evidence to date are also limited.…”

Section: Introductionmentioning

confidence: 99%

The Role of Temporary Appliances in Obstructive Sleep Apnea Treatment

Adame¹,

Cantwell²,

Le³

et al. 2023

J Dent Sleep Med

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Evaluation of prefabricated adjustable thermoplastic mandibular advancement devices (PAT-MADs) for obstructive sleep apnea: an Asian experience

Cited by 5 publications

References 15 publications

Efficacy of a Trial Oral Appliance in OSAS Management: A New Protocol to Recognize Responder/Nonresponder Patients

Efficacy of a Trial Oral Appliance in OSAS Management: A New Protocol to Recognize Responder/Nonresponder Patients

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

The Role of Temporary Appliances in Obstructive Sleep Apnea Treatment

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