Evaluation of Pregnant Women Susceptible to Cytomegalovirus Infection in Maiduguri, Nigeria

Abdullahi, Idris Nasir; Usman, Yahaya; Babayo, Adamu

doi:10.3923/jm.2015.336.342

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…The results of Nasir et al . 's[ 25 ] study in Nigeria showed that CMV seropositivity decreases significantly with the level of education. Hamdan et al .…”

Section: Discussionmentioning

confidence: 99%

Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort

Rezai

Rahimzadeh

Safar

et al. 2022

Advanced Biomedical Research

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Background: Congenital infections are among the most important conditions threatening human fetal health, the majority of which are caused by viral agents. Screening pregnant women for viral infections is essential because such infections can cause serious consequences for both the mother and the infant. So, this study aimed to serologically investigate sexually transmitted viral infections in pregnant women and also find the association between the prevalence of viral infections and epidemiological parameters in pregnant women of Sari, Iran. Materials and Methods: This descriptive, observational study was performed in pregnant women referring to Sari Birth Cohort Center between 2018 and 2020. A total of 1092 blood samples were investigated for hepatitis B (HBV), hepatitis C (HCV), human immunodeficiency virus (HIV), human T-lymphotropic virus (HTLV), and cytomegalovirus (CMV) serological markers by enzyme-linked immunosorbent assay (ELISA). Results: The prevalence of HBsAg positivity, HCV, HIV, and HTLV was 0.2%, 0.09%, 0.09%, and 0.2%, respectively. The percentage of participants with CMV-IgM and -IgG antibody titers above normal was 0.2% and 91.8%, respectively. Pregnant women whose educational level was bachelor's degree or lower, those who did not use a male condom before pregnancy, or those with a family history of infectious disease were found to be more likely to have HBV, HCV, HIV, HTLV, and CMV infections. Conclusion: Family history, maternal age, pregnancy stage, and not using a male condom are among the risk factors for sexually transmitted viral infections in pregnant women in Sari.

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“…The results of Nasir et al . 's[ 25 ] study in Nigeria showed that CMV seropositivity decreases significantly with the level of education. Hamdan et al .…”

Section: Discussionmentioning

confidence: 99%

Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort

Rezai

Rahimzadeh

Safar

et al. 2022

Advanced Biomedical Research

View full text Add to dashboard Cite

show abstract

“…In the Yemen research, the majority of respondents were illiterate, but there were no statistically significant differences between those of the CMV seropositive and those with low education (12). While research in Nigeria has shown that the degree of seronegativity in CMV increases significantly with the level of education (26).…”

Section: Discussionmentioning

confidence: 99%

Cytomegalovirus Infection in Pregnancy - Our Experiences

et al. 2019

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Introduction: Cytomegalovirus (CMV) infection is ubiquitous. It affects all age groups, and its clinical picture ranges from mild to severe, especially as a congenital infection in neonates. Aim: To determine frequency of CMV infection in pregnant women in Tuzla Canton (TC) and the risk factors that lead to the infection. Methods: This prospective study included 300 pregnant women from TC aged 18 to 42 years. CMV serology was performed on all participants, and in case of acute infection additionally IgG avidity test. Participants also completed the questionnaire on the risk factors for CMV infection. Results: The median age of the 300 women was 28 ±4.97 years. There were 161participants (53.6%) who classified their environment as urban and 295 (98.33%) were married. More than half of the women had completed secondary school 168 (56%). Positive IgG antibodies to CMV had 280 (93.0%) women. Positive IgM and IgG antibodies had 9 (3.0%) participants, but all of them had high IgG avidity, which indicates reinfection or recurrent CMV infection. There was a statistically significant higher number of seropositive participants living in rural areas than those living in urban areas (p= 0.048). Also, there was significantly higher percentage of positive anti-CMV IgG in pregnant women with lower education (p=0.04). Conclusion: In our region there is high seropositivity rates of IgG antibodies to CMV in pregnant women. No case of primary CMV infection was proven. The risk factors for CMV infection have been proven to be rural environment and lower level of education.

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Seroprevalence of Cytomegalovirus infection among pregnant women in some selected hospitals in Lokoja Metropolis, Kogi State, Nigeria

Bala¹,

Suleiman²,

M.B.³

2022

NJPAS

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Cytomegalovirus is one of the most common viruses which causes congenital defects in babies from infected mothers. Sensoneural hearing loss (SNHL) and neurodevelopmental delay are typical occurrences in childhood resulting from congenital defects which presents no symptoms at birth. The aim of this study was to determine the cytomegalovirus IgM infection among pregnant women attending antenatal clinics at KSSH and FMC in Lokoja metropolis, Kogi State, Nigeria. A total of 184 serum samples were collected and analyzed using CMV IgM ELISA kit diagnostic Automation, INC (USA). The study revealed that out of the 184 samples collected, 40 turned out positive for CMV IgM antibodies giving a prevalence of 21.7% while the negative sample result had a prevalence of 78.3%. a total of 92 samples each was collected from both hospitals; KSSH had 30 CMV IgM positive samples having a percentage 32.6% and FMC with 10 CMV IgM having a percentage of 10.86%. Based on the research, there was no significant association between the risk factors such as marital status, type of marriage, occupation and scarification related to the infection. This could be due to the limited number in sample size. Other socio-economic factors that had statistical significant p value with the infection were education (0.035), hand wash (0.027) and previous history of blood transfusion (0.003). The study has shown the need for sensitization of the populace especially to pregnant women, the need for constant and proper personal hygienic practices be done to reduce the risk of infection and possibly stop its transmission to fetus. In addition, inclusion of screening for cytomegalovirus antibodies among blood donors may be useful tool in preventing transmission of cytomegalovirus to blood recipients.

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Evaluation of Pregnant Women Susceptible to Cytomegalovirus Infection in Maiduguri, Nigeria

Cited by 3 publications

References 19 publications

Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort

Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort

Cytomegalovirus Infection in Pregnancy - Our Experiences

Seroprevalence of Cytomegalovirus infection among pregnant women in some selected hospitals in Lokoja Metropolis, Kogi State, Nigeria

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