Evaluation of prescription pattern of fixed-dose combinations in a tertiary care hospital in India - A cross-sectional study

Belhekar, Mahesh N; Bhave, Kiran; Patel, Tejal; Pandit, Prasad R.; Mandaknalli, Saurabh L; Mundada, Krishna

doi:10.5455/njppp.2019.9.01031105032019

Cited by 2 publications

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“…[14] 145 out of 400 prescriptions (36.25%) were found to be containing Fixed Dose Combination (FDC) in present study, the nding which coincides with the results reported by Belhekar MN et al Since FDCs reduce the actual quantity of dosage forms to be taken by the patient, it helps to improve the adherence to treatment by increasing compliance of the patients . 78.46 % drugs were found to be prescribed from the [15] National List of Essential Medicines (NLEM) 2015 and 67.22 % drugs were from WHO List of essential medicine 2019 in this study. Another study conducted by Mittal N et al has also revealed the similar ndings [16] .…”

Section: B) Gender-wise Distribution Of Study Participantsmentioning

confidence: 67%

A Study of Drug Utilization and Potential Drug-Drug Interactions in Outpatient Pharmacy of a Tertiary Care Teaching Hospital: A Cross-Sectional Observational Study.

Deshmukh

Dabhade

2020

IJAR

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Introduction: Drug utilization research evaluates the appropriateness of the prescriptions which is important in clinical practice. Hospital Pharmacy is the place where the data of prescriptions from all the Outpatient departments of the hospital can be gathered under one roof. Methodology: A cross-sectional, observational study was carried out in the Outpatient pharmacy of a tertiary care teaching hospital. The study was conducted over a period of 1 month on 400 prescriptions. Results: Average no of drugs per prescription was 2.40 ± 1.49. 30.25% of prescriptions contained an antibiotic. Beta lactam was the most commonly prescribed class of antibiotics, while Coamoxiclav was the most commonly prescribed antibiotic drug. 78.46% and 67.22% of the drugs were prescribed from NLEM and WHO list, respectively. Total 130 pDDIs were observed in all the 400 prescriptions surveyed, out of which 51 prescriptions were showing at least one pDDI. Conclusion: The rate of prescription of drugs from both the Essential drug lists was satisfactory. No injection was prescribed on OPD basis. Almost 87 % prescriptions were not having any potential drug-drug interaction (pDDI). All these observations highlight the rational prescription of drugs as per WHO Drug use indicators. The study highlights the need to minimize the percentage of antibiotics prescribed. Further studies are warranted to analyse the causes of Polypharmacy observed in some prescriptions in this study and to find ways to minimize it as much as possible.

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Section: B) Gender-wise Distribution Of Study Participantsmentioning

confidence: 67%