“…Two independent reviewers read to the title of them and removed 138 irrelevant studies. The reviewers read the abstract of the remaining studies and excluded 12 studies because of dentin microhardness, sealer dentin tubules penetration (Antunes et al, 2019; Aydin et al, 2016; Aydın et al, 2019; Bayram et al, 2017; Choudhury et al, 2020; Gokturk & Ozkocak, 2022; Gyulbenkiyan et al, 2020; Kesim et al, 2018; Prasanthi et al, 2019; Ratih, Sari, et al, 2020), has not EDTA group (Silva et al, 2012), and lack of a SEM study (Mathew et al, 2017). Finally, 15 studies for the full‐text assessment were analyzed and only seven studies (Darrag, 2014; İlhan, 2019; Kamble et al, 2017; Kaur et al, 2020; Madhusudhana et al, 2015; Penumaka et al, 2019; Sari et al, 2018) were considered eligible.…”