Evaluation of Quality of Life of Adult Patients with Celiac Disease in Argentina: From Questionnaire Validation to Assessment

Selleski, Nicole; Zandonadi, Renata Puppin; Milde, Laura; Gandolfi, Lenora; Pratesi, Riccardo; Haüser, Winfried; Uenishi, Rosa Harumi; Nakano, Eduardo Yoshio; Pratesi, C

doi:10.3390/ijerph17197051

Cited by 13 publications

(19 citation statements)

References 39 publications

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“…The mean F-CDQ total score for the whole population was 73 (±12), with “Social” and “Gastrointestinal Symptoms” being the least affected subdomains. This total score should be considered as high, in agreement with results previously reported [ 21 , 22 ]. It seems possible to establish a link between the low rate of “Gastrointestinal Symptoms” and the high compliance with the GFD.…”

Section: Discussionsupporting

confidence: 91%

“…Diet compliance is an independent factor improving CD patients’ QOL, and finding the tools to facilitate this adherence remains a challenge. Several studies suggest that educational interventions can improve the management of CD and perceived QOL [ 21 , 26 ]. As far as demographic factors are concerned, women had a lower QOL than men, consistent with previous studies [ 21 , 28 , 37 , 38 ].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies suggest that educational interventions can improve the management of CD and perceived QOL [ 21 , 26 ]. As far as demographic factors are concerned, women had a lower QOL than men, consistent with previous studies [ 21 , 28 , 37 , 38 ]. However, studies in the general population of Western countries have reported a lower QOL in women than in men, so this difference may not be related to the impact of CD on QOL [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

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Compliance with Gluten Free Diet Is Associated with Better Quality of Life in Celiac Disease

et al. 2022

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The quality of life (QOL) of patients with celiac disease (CD) can be altered by both symptoms of the disease and by the restrictions of the gluten-free diet (GFD). The objective was to determine the factors associated with better QOL in a large cohort of CD patients. A link to an online survey was sent to the members of the French Association of Gluten Intolerant People (AFDIAG). The French-Celiac Disease Questionnaire (F-CDQ), scoring from 0 to 100, was used to measure the QOL. Other data collected were sociodemographic characteristics, information on CD, purchasing and consumption habits of gluten-free products, and a self-assessment scale (ranging from 0 to 10) to determine the compliance with the GFD. Among the 907 CD patients who returned the questionnaire, 787 were analyzed (638 women (81%); median age: 49 years; 71% with self-assessed GFD compliance > 8). Their median F-CDQ was 73 (range: 59–82). In multivariate analysis, the main factors associated with a better quality of life were the long duration of the GFD, good compliance with the GFD, and the number of follow-up visits. Compliance with and duration of the GFD are associated with a better quality of life in patients with CD. Taking this into consideration would offset its restrictive aspect and improve its adherence.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Compliance with Gluten Free Diet Is Associated with Better Quality of Life in Celiac Disease

et al. 2022

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“…In Italy, the lower age was the only clinical variable that affected the QOL of CD children and their parents [ 23 ]. A study from Argentina reported a higher score of health-related QOL among those people who admit having knowledge of CD related national regulations and benefits [ 24 ]. The health-related QOL for Saudi CD children on GFD was generally comparable to the healthy control, except for the general health domain [ 25 ].…”

Section: Suggested Causes For the Recent Increase In CD Incidencementioning

confidence: 99%

Celiac disease in the COVID-19 pandemic

Samaşcă¹,

Lerner²

2021

Journal of Translational Autoimmunity

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Background The COVID-19 pandemic has had an impact on global health. Design The impact of the COVID-19 pandemic on patients with coeliac disease was assessed in the present review. Results The incidence of coeliac disease and the problems associated with coeliac disease increased during the COVID-19 pandemic. Adherence to the diet is crucial for the patient's health and quality of life since the only approved therapy for coeliac disease is a gluten withdrawal. Conclusions A gluten-free diet should be promoted by the therapeutic team and implemented among these categories of patients.

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“…To date, in Spain, only CD–QoL has been adapted and validated by comparison with EQ–5D ( 18 ). The CDQ original version is from Germany, since then has been adapted and validated in France, Turkey, Italy, Iran, and more recently in Argentina with good psychometric properties ( 19 – 23 ). The CDQ also has been adapted and validated in Brazil and Poland ( 24 , 25 ).…”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Teenagers and Adults With Coeliac Disease: From Newly Spanish Coeliac Disease Questionnaire Validation to Assessment in a Population-Based Study

2022

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BackgroundCoeliac disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten in genetically predisposed individuals. Gluten restriction in CD sufferers leads to numerous limitations in various aspects of daily life and can significantly impact the quality-of-life (QoL). The specific and widely used Coeliac Disease Questionnaire (CDQ) is an excellent tool to evaluate QoL in patients with CD, assessing physical, psychological, and social domains. This questionnaire is unavailable in Spain. Therefore, our study is the first to translate, culturally adapt, validate, and apply the Spanish version of CDQ to a representative sample of Spanish teenagers and adults with CD.MethodsA total of 153 CD participants with biopsy-proven and self-reported gluten-free adherence were included in the cross-sectional study, which included four stages: (1) translation and retranslation of the French CDQ version into Spanish; (2) cultural adaptation and semantic evaluation; (3) CDQ validation through the internal consistency determination and reproducibility of the QoL; and (4) application of the questionnaire to Spanish teenagers and adults with CD and estimation of QoL using EQ-5D.ResultsThe internal consistency and test–retest reliability of the Spanish CDQ were satisfactory and no ceiling or floor effects were detected. Significant correlations were identified between the CDQ scales, and the instrument for validation covering similar dimensions of the QoL was identified. The mean CDQ total score was 131.03 ± 24.1, and the social domain had the highest rating. There was no correlation between the time spent on a gluten-free diet and QoL. A significantly higher QoL score was reported among males and adolescents in the 15–17 age groups.ConclusionThe newly Spanish CDQ is an appropriate tool to assess the QoL of the teenager and adult patients with CD. This study highlights the importance of identifying the affected scales to address actions to reduce the impact of the gluten-free diet burden of the coeliac patients and maintain public health regulations that support patients with chronic diseases such as CD.

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Evaluation of Quality of Life of Adult Patients with Celiac Disease in Argentina: From Questionnaire Validation to Assessment

Cited by 13 publications

References 39 publications

Compliance with Gluten Free Diet Is Associated with Better Quality of Life in Celiac Disease

Compliance with Gluten Free Diet Is Associated with Better Quality of Life in Celiac Disease

Celiac disease in the COVID-19 pandemic

Quality of Life in Teenagers and Adults With Coeliac Disease: From Newly Spanish Coeliac Disease Questionnaire Validation to Assessment in a Population-Based Study

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