Evaluation of Radiosurgery Target Volume Determination for Meningiomas Based on Computed Tomography (CT) And Magnetic Resonance Imaging (MRI)

Abstract

Objective: Meningiomas arise from arachnoid cap cells and comprise the commonest benign tumor of the brain, accounting for more than one third of all intracranial neoplasms. Surgery and radiation therapy (RT) have been traditionally used in meningioma management. Radiosurgery is a sophisticated form of therapeutic irradiation with the capability of delivering high doses of radiation to well defined targets with typically steep dose gradients around the treatment volumes under robust stereotactic localization and image guidance. Target volume definition is an important part of menigioma radiosurgery. In this study, we assessed the use of multimodality imaging for target volume definition in radiosurgery of meningiomas. Methodology:We included 27 patients receiving meningioma radiosurgery at our department. All patients were treated with high precision radiosurgery after multidisciplinary assessment of patients regarding lesion size, location, association with critical neurovascular structures, symptomatology, and previous treatments. Target volume determination was done based on using only CT images and also by incorporation of MR fusion to perform a comparative assessment. Results:Comparative evaluation revealed improved target volume definition by incorporation of MRI into radiosurgery treatment planning for patients treated with radiosurgery for meningiomas. Conclusion:Improved target definition is a pertinent goal of optimal radiosurgical treatment planning. Our study supports the utility of MRI in meningioma radiosurgery treatment planning. Clearly, further research is warranted to refine target definition for radiosurgical management of meningiomas.

Evaluation of Radiosurgery Target Volume Definition for Tectal Gliomas with Incorporation of Magnetic Resonance Imaging (MRI): An Original Article

“…Utility of multimodality imaging for radiosurgery treatment planning for tectal gliomas has been poorly addressed in the literature. In this context, our study adds to the existing literature and supports the incorporation of MRI for improved radiosurgery treatment planning for tectal gliomas consistent with another studies [48][49][50][51][52][53][54][55][56][57][58][59].…”

Utility of Multimodality Imaging Based Target Volume Definition for Radiosurgery of Trigeminal Neuralgia: An Original Article

“…In this study, we assessed incorporation of multimodality imaging into target volume definition of trigeminal neuralgia radiosurgery. Indeed, usefulness of neuroimaging with MRI for definition of central nervous system radiotherapy and radiosurgery target volumes has been an important focus of research in the literature [40][41][42][43][44][45][46][47][48][49]. Our results appear to be compatible to these studies supporting the incorporation of MRI in radiosurgery treatment planning.…”

Determination of Radiosurgery Treatment Volume for Intracranial Germ Cell Tumors (GCTS)

“…In this context, multimodality imaging may add to the accuracy of target definition for radiosurgery of intracranial GCTs. Indeed several other studies have demonstrated refined treatment volume determination by including MRI to the process of target determination [39][40][41][42][43][44][45][46][47][48][49][50][51].…”