In this paper, stress analysis of the welded incline-bent pipe under non-operating condition and operating condition has been analyzed by the means of ANSYS finite element analysis. The results show that the maximum stress of the welded incline-bent pipe is 0.29Mpa at 0.88m of the lower end under the combined action of bending moment. The maximum stress of is 4250MPa at 0.24m around the corner under the joint action of bending moment, internal media pressure and temperature field. Compared to two kinds of conditions found welded incline-bent pipe both at the corner weld of larger stress concentration, and the maximum stress in the operating condition is 15,000 times of the maximum stress under the non-operating condition. Thus the welded incline-bent pipe should try to reduce the additional bending moment and avoid to produce larger stress concentration. In this way, the safety of the welded incline-bent pipe is improved under the condition of installation. The results of this investigation provide some reference for the design of engineering piping.