Evaluation of rigid gas permeable lens fitting in keratoconic patients with optical coherence tomography

Elbendary, Amal M.; Samra, Waleed Abou

doi:10.1007/s00417-013-2271-1

Cited by 20 publications

(10 citation statements)

References 22 publications

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“…OCT facilitates a highly precise cross‐sectional assessment of the interaction between the anterior corneal surface and a contact lens in situ . OCT has been applied to measure central and peripheral tear film clearance in patients with keratoconus fitted with different rigid lens configurations (that is, three‐point‐touch, apical clearance and apical bearing) . The quantification of corneal vault, across the diameter of a contact lens, is useful for fitting other modalities, including mini‐scleral (Figure A) and hybrid lenses (Figure B).…”

Section: New Imaging Technology and Its Role In Contact Lens Fitting mentioning

confidence: 99%

“…OCT has been applied to measure central and peripheral tear film clearance in patients with keratoconus fitted with different rigid lens configurations (that is, three-pointtouch, apical clearance and apical bearing). 135 The quantification of corneal vault, across the diameter of a contact lens, is useful for fitting other modalities, including mini-scleral ( Figure 9A) and hybrid lenses ( Figure 9B). Such an approach is particularly useful in keratoconus, where asymmetric clearance across the lens is relatively common due to the irregularity of the corneal profile.…”

Section: Optical Coherence Tomographymentioning

confidence: 99%

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Contact lens management of keratoconus

Downie

Lindsay²

2015

Clinical and Experimental Optometry

137

103

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Contact lenses are the primary form of visual correction for patients with keratoconus. Contemporary advances in contact lens designs and materials have significantly expanded the available fitting options for patients with corneal ectasia. Furthermore, imaging technology, such as corneal topography and anterior segment optical coherence tomography, can be applied to both gain insight into corneal microstructural changes and to guide contact lens fitting. This paper provides a comprehensive review of the range of contact lens modalities, including soft lenses, hybrid designs, rigid lenses, piggyback configurations, corneo-scleral, mini-scleral and scleral lenses that are currently available for the optical management of keratoconus. The review also discusses the importance of monitoring for disease progression in patients with keratoconus, in particular children, who tend to undergo more rapid progressive changes, so as to facilitate appropriate modification to contact lens fitting and/ or potential referral for corneal collagen cross-linking treatment, as appropriate.

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Section: New Imaging Technology and Its Role In Contact Lens Fitting mentioning

confidence: 99%

Section: Optical Coherence Tomographymentioning

confidence: 99%

Contact lens management of keratoconus

Downie

Lindsay²

2015

Clinical and Experimental Optometry

137

103

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“…The RGP lens has a unique fitting method with "apical touch" (the lens to the corneal apex), intermediate clearance, and a band of touch at the junction of the optical zone and the secondary curve. The relationship between the lens edge and the cornea is another significant factor influencing optimal lens fitting and determining patient comfort and maximum wearing time [25,26]. Most studies on ocular surface shape only investigated the central cornea, which is the most important factor for vision.…”

Section: Clinical Uses In CL Practicementioning

confidence: 99%

“…A large proportion of CL drop-outs cite discomfort and symptoms of dryness as reasons for ceasing lens wear [43][44][45][46]. If the post-lens tear layer is diminished, as in tight lens fitting or dry eye syndrome, the accumulation of debris and dead cells may pose a significant risk to the ocular surface [25,31]. A thorough assessment of the tear film allows a more suitable lens material to be selected, such as one with a low water content (to limit dehydration) and high lubricity (to minimize friction), which are associated with a positive impact on CL comfort.…”

Section: Evaluation Of Tear Fluid In CL Wearersmentioning

confidence: 99%

Developments in Contact Lens Imaging: New Applications of Optical Coherence Tomography

et al. 2019

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Optical coherence tomography (OCT) is a high-speed and non-contact optical imaging technology widely used for noninvasive cross-sectional imaging of biological objects. Two main OCT technologies have been developed: time domain and Fourier domain technologies. The latter can be further divided into spectral domain OCT, which uses a broadband light source and a spectrometer as a detector, and swept source OCT, which employs a quickly-rotating laser source. Advances in OCT technology have made it one of the most helpful devices in ophthalmic practice. Fourier OCT has revolutionized imaging of the posterior segment of the eye, as well as of anterior structures and has enhanced the ability to diagnose and manage patients. It provides high-resolution information about the tear film, contact lens (CL), a qualitative and quantitative assessment of the anterior eye that is important in contact lens fitting, and allows possible eye surface changes while wearing contact lenses to be monitored. Potential swept source OCT technology applications include industrial processes of lens design and quality control. In this paper, we describe clinical applications and outline a variety of multifunctional uses of OCT in the field of refractive error correction with contact lenses.

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“…Soft contact lenses have large diameters, beyond the limbus with a slightly movement during blinking (MaldonadoCodina and Efron, 2004;Wolffsohn et al, 2013). Nevertheless, rigid gas permeable lenses have a small diameter with more edge lift and movement than soft contact lenses, provoking more discomfort during the wearing (Brennan et al, 1987;Carracedo et al, 2015a;Cornish and Sulaiman, 1996;Elbendary and Abou Samra, 2013;Fink et al, 1992). Both contact lenses are bearing over the cornea Currently, there is a rigid gas permeable special design, called mini scleral lens and mainly indicated for keratoconus and severe dry eye which does not bear over the cornea, keeping a post lens tear meniscus between the cornea and the lens.…”

Section: Presence In Contact Lens Wearersmentioning

confidence: 99%

The role of dinucleoside polyphosphates on the ocular surface and other eye structures

Carracedo

Crooke

Guzmán-Aránguez

et al. 2016

Progress in Retinal and Eye Research

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a b s t r a c tDinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present in tears, aqueous humour and in the retina. As the consequence of their presence, these dinucleotides contribute to many ocular physiological processes. On the ocular surface, dinucleoside polyphosphates can stimulate tear secretion, mucin release from goblet cells and they help epithelial wound healing by accelerating cell migration rate. These dinucleotides can also stimulate the presence of proteins known to protect the ocular surface against microorganisms, such as lysozyme and lactoferrin. One of the latest discoveries is the ability of some dinucleotides to facilitate the paracellular way on the cornea, therefore allowing the delivery of compounds, such as antiglaucomatous ones, more easily within the eye. The compound Ap 4 A has been described being abnormally elevated in patient's tears suffering of dry eye, Sjogren syndrome, congenital aniridia, or after refractive surgery, suggesting this molecule as biomarker for dry eye condition. At the intraocular level, some diadenosine polyphosphates are abnormally elevated in glaucoma patients, and this can be related to the stimulation of a P2Y 2 receptor that increases the chloride efflux and water movement in the ciliary epithelium. In the retina, the dinucleotide dCp 4 U, has been proven to be useful to help in the recovery of retinal detachments. Altogether, dinucleoside polyphosphates are a group of compounds which present relevant physiological actions but which also can perform promising therapeutic benefits.

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Evaluation of rigid gas permeable lens fitting in keratoconic patients with optical coherence tomography

Cited by 20 publications

References 22 publications

Contact lens management of keratoconus

Contact lens management of keratoconus

Developments in Contact Lens Imaging: New Applications of Optical Coherence Tomography

The role of dinucleoside polyphosphates on the ocular surface and other eye structures

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