Evaluation of Safe Infusion Devices for Antineoplastic Administration

Abstract

Nurses endure daily low-level exposure to cytotoxic drugs, which can lead to significant absorption with potential harmful consequences. New sterile medical devices called cytotoxic safe infusion systems (CSISs), intended by their manufacturers to improve safety and quality of cytotoxic drug infusions, have been made commercially available. CSISs from 3 manufacturers were tested in 2 cancer units and compared with standard infusion sets. The aim of this study is to evaluate the devices regarding occupational exposure, quality of the infusion, and economic aspects.

Assessment of Occupational Exposures to Antineoplastic Drugs in a Hospital of High Complexity

“…Assessment of healthcare workers exposure to antineoplastic drugs is still a challenging issue since new, critical, and emerging factors can expose pharmacists who prepare hazardous drugs or nurses who administer anticancer agents to an increased risk of developing adverse health effects (Sottani et al, 2012). Studies over the past two years have mainly focused: monitoring and exposure (Capron et al,2012, Lalande et al, 2012, Wakui et al,2013, Kopp et al, 2013, Bobin-Dubigeon et al, 2013, Zhang et al,2013 and analysis of the consequences of exposure (El-Ebiary et al, 2013, Moretti et al, 2014, Ladeira et al, 2014, Connor et al, 2014.…”