Evaluation of Safety and Efficacy of Barrier Foam Dressing in Patients with Exuding Wounds

Abstract

Objective: The study was conducted to evaluate the safety, efficacy and tolerability of Barrier Foam Dressing (BFD) combined with ammonium Polyquaternary compoundpoly(DADMAC) with regard to effect on wound characteristics i.e., size, discharge, granulation; extent of dressing breakthrough in exuding wounds, pain and time to wound closure by epithelization or readiness for secondary suturing or skin grafting. Material and Methods:The study was an open labeled single center trial of 30 patients with wound or wounds of different etiologies. The patients satisfying inclusion and exclusion criteria as specified in the protocol approved by the Ethical Committee, were enrolled. The wound was evaluated on the basis of size, discharge and granulation at baseline and on every 8th day along with wound photograph till the end point. Microbial analysis of the wound swab and pain score (using Visual Analog Scale -VAS) was recorded at baseline and at the end point of study. Improvement in wound healing was observed by contraction of wound, reduction in exudate, wound debridement and as wound epithelisation, or granulation tissue formation that makes the wound ready to receive a skin graft.Results: BFD was observed to have good ability to absorb wound exudate, help separation of necrotic tissue making debridement easier. Minimal adherence was noticed while removing the dressing. There was no need of any topical antimicrobial along with this dressing. Biochemical and microbiological variables also exhibited the safety and efficacy of this dressing. Its application on skin surface was well tolerated without side effects or local reaction by all except one of the patients. Conclusion:The BFD can be used as a primary dressing for various types of wounds and has favorable influence on wound healing process with good tolerance.

Experience of Wound Bed Preparation with Different Methods

“…An open-labeled study was conducted by the author to evaluate the safety and efficacy of barrier foam dressing. The study details and the outcome has been published [19].…”