2019
DOI: 10.1186/s40249-019-0566-0
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of scrub typhus diagnosis in China: analysis of nationwide surveillance data from 2006 to 2016

Abstract: Background Scrub typhus is a life-threatening disease caused by Orientia tsutsugamushi , and specific antimicrobial medicine is available . Early and accurate diagnosis is essential for reducing the risk of severe complications and death. In this study, we aimed to evaluate the case diagnosis situation among medical care institutions and geographical regions in China, and the results will benefit both clinical practice and the disease surveilla… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
18
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 17 publications
(18 citation statements)
references
References 33 publications
0
18
0
Order By: Relevance
“…However, other diseases, such as spotted fever group of rickettsioses, insect bites (including spider bites), posttraumatic scabs and anthrax, can include an inoculation eschar at the surface of the skin (Xin et al, 2019). All these diseases associated with an eschar could increase the chance of misdiagnosis and influence the accuracy of our results.…”
Section: Discussionmentioning
confidence: 94%
“…However, other diseases, such as spotted fever group of rickettsioses, insect bites (including spider bites), posttraumatic scabs and anthrax, can include an inoculation eschar at the surface of the skin (Xin et al, 2019). All these diseases associated with an eschar could increase the chance of misdiagnosis and influence the accuracy of our results.…”
Section: Discussionmentioning
confidence: 94%
“…The drug of choice for the treatment of scrub typhus is doxycycline (tetracycline, chloramphenicol, and azithromycin have also been used successfully) [6][7][8]; however, the emergence of antibiotic-resistant strains of O. tsutsugamushi is of concern [9]. Additionally, there are no long-lasting, broadly protective vaccines available against scrub typhus [10].…”
Section: Introductionmentioning
confidence: 99%
“…tsutsugamushi is of concern [ 9 ]. Additionally, there are no long-lasting, broadly protective vaccines available against scrub typhus [ 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…The disease is transmitted by chigger mites (larval trombiculid mites) infected with the gram-negative intracellular rickettsial bacterium Orientia tsutsugamushi bacteria [1][2][3] . Human diseases can range from mild (asymptomatic) to lethal, and are generally u-like (fever, headache, myalgia) in their symptomology 4,5 . Rodents, the primary hosts of mites, are thus indispensable for the survival of chiggers and play a key role in the transmission of ST 3,6−8 .…”
Section: Introductionmentioning
confidence: 99%
“…Recent evidence from China indicated that ST has expanded to all the provinces across both rural and urban areas, and the incidence of ST has increased in an unprecedented manner, in both historically endemic areas and in new areas not previously identi ed as having cases 18 . Jiangxi province, a relatively new epidemic focus of ST in southeastern China, has gradually developed into one of the most seriously affected provinces for the disease 5 , with the increase in the number of cases and geographic expansion of ST 18 . Since the rst case of ST reported Shanggao county in 1998 19 , the ST epidemic has rapidly spread 48 counties in 2016 according to the national ST surveillance data 18 .…”
Section: Introductionmentioning
confidence: 99%