Evaluation of sex‐related changes in skin topography and structure using innovative skin testing equipment

Dąbrowska, Marta; Mielcarek, A.; Nowak, Izabela

doi:10.1111/srt.12473

Cited by 20 publications

(20 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In accordance with the findings of Dąbrowska et al, (2018), the present results revealed significant differences in the skin surface and structure between males and females . These authors found that the skin of women had more abundant superficial skin lines and wrinkles in comparison with male skin, which was in agreement with previous literature reporting that men's skin had a lower number of wrinkles .…”

Section: Discussionsupporting

confidence: 93%

In vivo determination of the skin surface topography and biophysical properties of human hands: Effects of sex and hand dominance

Enright

Nikolis

2019

Skin Research and Technology

View full text Add to dashboard Cite

Background The effect of hand dominance on the skin topography and parameters associated with skin health and aging is unknown. Methods Healthy adult volunteers were recruited. The following four strata were enrolled: Group 1: male, right handed; Group 2: male, left handed; Group 3: female, right handed; and Group 4: female, left handed. The differences between groups on their surface evaluation of living skin (SELS) parameters were evaluated. These variables included (a) roughness (SER); (b) smoothness (SESM); (c) scaliness (SESC); and (d) wrinkles (SEW). Results A total of twenty subjects were recruited, with five in each stratum. Significant differences between groups were found for SESC [F(7,31) = 2.742, P = .024, partial eta squared = 0.382] and SEW [F(7,31) = 3.705, P = .005, partial eta squared = 0.456]. An evaluation of the descriptive statistics revealed that males had a higher mean SESC value than females and a lower mean SEW value. Moreover, the dominant hand of both sexes had a higher mean SEW value than non‐dominant hands. Conclusions Given the evidence of sex and handedness differences in wrinkle genesis and desquamation severity, these factors should be considered in the dermatological treatment and counseling of patients.

show abstract

Section: Discussionsupporting

confidence: 93%

In vivo determination of the skin surface topography and biophysical properties of human hands: Effects of sex and hand dominance

Enright

Nikolis

2019

Skin Research and Technology

View full text Add to dashboard Cite

show abstract

“…All equipment was purchased from Courage + Khazaka electronic GmbH (Köln, Germany). The importance of technical possibilities of the above-mentioned devices concerning selected skin parameters have been described comprehensively in the authors’ previous publications [ 21 , 22 ].…”

Section: Methodsmentioning

confidence: 99%

Lipid Nanoparticles Loaded with Selected Iridoid Glycosides as Effective Components of Hydrogel Formulations

Dąbrowska¹,

Nowak²

2021

Materials

Self Cite

View full text Add to dashboard Cite

One possibility of improving active ingredient penetration into deeper skin layers to enhance the cosmetic product effectiveness, is the application of lipid nanoparticles. The aim of the study presented in this paper was to evaluate the potential of hydrogel formulations enriched with iridoid glycosides-loaded lipid nanoparticles. Lipid nanocarriers were produced using an emulsification-ultrasonication method based on multiple emulsions. The encapsulation efficiency was determined at the level of 89% and 77% for aucubin and catalpol, respectively. The next stage was the incorporation of the obtained dispersions of lipid nanoparticles into hydrogel formulations, followed by determination of their physicochemical properties, shelf-life stability, and application properties (in vivo tests). The introduction of lipid nanoparticles increased the stabilization of the consistency of the obtained hydrogel formulations, and was confirmed by viscosity measurements. No effect of lipid nanoparticle incorporation on shelf-life stability of the hydrogels was detected. In vivo studies showed improvements in moisture content of the epidermis, transepidermal water loss, skin topography, and macrorelief parameters. In particular, a synergistic effect of the active ingredients and lipid nanoparticles on the anti-wrinkle effect, moisturizing effect, and regeneration of the protective barrier of the stratum corneum was evidenced. The attractiveness of aucubin and catalpol as cosmetic raw materials in hydrogel formulations was evidenced, especially when the iridoid glycosides were applied in the form of lipid nanoparticles.

show abstract

“…The numbers of enlarged facial pores were determined by applying the “small” filter, as the small filter of the Antera 3D® is well correlated with visual perception and sensitive enough to distinguish changes caused by application of cosmetic products 27 . An Ultrascan UC22 (Courage + Khazaka Electronic) was used to evaluate the dermal density of the skin before and after application of products 28 . A Vivascope 1500 (Caliber ID Rochester) confocal laser scanning microscope (CLSM) was used to examine the inner skin structures from the stratum corneum to the epidermal‐dermal interface in vivo noninvasively.…”

Section: Methodsmentioning

confidence: 99%

“…27 An Ultrascan UC22 (Courage + Khazaka Electronic) was used to evaluate the dermal density of the skin before and after application of products. 28 A Vivascope 1500 (Caliber ID Rochester) confocal laser scanning microscope (CLSM) was used to examine the inner skin structures from the stratum corneum to the epidermal-dermal interface in vivo noninvasively. CLSM uses a laser source with a wavelength of 830 nm, illumination power up to 22.1 mW on the object, and water-based gel as the immersion media.…”

Section: Instrumentsmentioning

confidence: 99%

Reduction of enlarged facial pore using ion‐paired amino acid through enhancement in skin permeation and exfoliation: A placebo‐controlled in vivo study

Kwon¹,

Lee²,

Kim³

et al. 2020

J of Cosmetic Dermatology

View full text Add to dashboard Cite

The stratum corneum (SC) is composed of corneocytes and a lipid matrix and forms the outermost layer of the skin. Corneocytes consist of a cornified envelope and keratin fiber and are connected to each other via corneodesmosome junctions. 1 The human SC is composed of 15-20 layers of cells formed in the basal layer of the epidermis. These cells are pushed toward the outmost layer of the skin where they are desquamated resulting in epidermal homeostasis. 2,3 Desquamation is assisted by the serine proteases kallikrein 5 and

show abstract

Evaluation of sex‐related changes in skin topography and structure using innovative skin testing equipment

Abstract: Non-invasive methods of skin testing using new and advanced equipment have provided a possibility of objective parametrization and evaluation of sex-related changes in skin topography and structure.

Cited by 20 publications

References 18 publications

In vivo determination of the skin surface topography and biophysical properties of human hands: Effects of sex and hand dominance

In vivo determination of the skin surface topography and biophysical properties of human hands: Effects of sex and hand dominance

Lipid Nanoparticles Loaded with Selected Iridoid Glycosides as Effective Components of Hydrogel Formulations

Reduction of enlarged facial pore using ion‐paired amino acid through enhancement in skin permeation and exfoliation: A placebo‐controlled in vivo study

Contact Info

Product

Resources

About