2018
DOI: 10.1016/j.cca.2018.09.026
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Evaluation of sex-specific cut-off values of high-sensitivity cardiac troponin I and T assays in an emergency department setting – Results from the Linz Troponin (LITROP) study

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Cited by 19 publications
(13 citation statements)
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“…4c and Supplementary Table S2), and this is better than the 99th percentile cutoff value (28 pg/mL) in a healthy population used for the clinically approved cardiac troponin assay. 29,30 Importantly, the nanocomposite coated biosensor also showed ultra-high selectivity with no background signal for commonly found interfering molecules in biological samples, such as uric acid, dopamine, and tryptophan (Supplementary Fig. S4).…”
Section: Ultra-sensitive Analytical Performance Of the Nanocomposite-coated Ec Sensormentioning
confidence: 98%
“…4c and Supplementary Table S2), and this is better than the 99th percentile cutoff value (28 pg/mL) in a healthy population used for the clinically approved cardiac troponin assay. 29,30 Importantly, the nanocomposite coated biosensor also showed ultra-high selectivity with no background signal for commonly found interfering molecules in biological samples, such as uric acid, dopamine, and tryptophan (Supplementary Fig. S4).…”
Section: Ultra-sensitive Analytical Performance Of the Nanocomposite-coated Ec Sensormentioning
confidence: 98%
“…Studies examined this relationship with regard to the performance and prognostic significance of gender-specific cutoffs for cTnT and cTnI [ 14 ]. One effect seems to be particularly evident in women: for cTnI, the use of gender-specific cutoffs led to a significant increase in the diagnosis of myocardial injury in women, while in men, this diagnosis decreased only marginally [ 22 , 23 , 24 ]. This finding matches with our retrospective data.…”
Section: Discussionmentioning
confidence: 99%
“… 1 In humans, male sex is positively associated with cTnI concentration, and sex-specific reference intervals (RIs) are used. 9 11 Breed differences have been found in healthy dogs, 12 , 13 and a previous report in cats with hypertrophic cardiomyopathy (HCM) indicated a breed effect. 14 In healthy cats, cTnI concentrations have neither been associated with sex nor with breed or body condition score (BCS).…”
Section: Introductionmentioning
confidence: 95%