Evaluation of short-lived atmospheric fine particles in Tehran, Iran

Borhani, Faezeh; Motlagh, Majid Shafiepour; Ehsani, Amir Houshang; Rashidi, Yousef

doi:10.1007/s12517-022-10667-5

Cited by 13 publications

(3 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Numerous recent studies across Iran have been conducted in this context. [4][5][6] The quality of air in Iran is a serious issue, as some major cities such as Tehran, Mashhad, Tabriz, Isfahan, Ahvaz and Arak have very high levels of air pollutants. Mashhad, which is the second biggest religious city in the world, is also one of the most polluted cities in Iran.…”

Section: Introductionmentioning

confidence: 99%

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Rafiee,

Miri,

Taghavi

2024

Journal of Advances in Environmental Health Research

View full text Add to dashboard Cite

Background: Air pollution stands as a significant environmental threat impacting human health across the globe, encompassing both developed and developing nations. This study aimed to survey the temporal variations of PM2.5 and gauge its potential health effects in the city of Mashhad over the period of 2010-2018. Methods: This cross-sectional study was carried out among the residents of Mashhad city. PM2.5 concentration data spanning the years 2008-2019 were collected and subjected to analysis using Excel and AirQ software. Results: The results indicate that the highest concentration of PM2.5 was associated with the year 2010, while the lowest concentration was observed in 2015. The analytical findings demonstrated that for each 10 µg/m3 increase in PM2.5 concentrations, the relative risk for total mortality increased by 10.47%. Furthermore, based on the Air Quality Index (AQI) results, 2010 exhibited the most adverse condition in terms of PM2.5 concentrations in Mashhad city. Conclusion: In general, long-term exposure to ambient PM2.5 significantly contributed to mortality in the megacity of Mashhad. As air pollution is a modifiable risk factor, it is advisable to implement sustainable control policies to protect public health.

show abstract

Section: Introductionmentioning

confidence: 99%

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Rafiee,

Miri,

Taghavi

2024

Journal of Advances in Environmental Health Research

View full text Add to dashboard Cite

show abstract

“…While this is beneficial for the country’s economy, sudden population expansion in Tehran has increased air pollution and threatened human health, agricultural productivity, and the ecosystem. Short-lived climate-forced ozone, the major photochemical oxidant, is one of the primary hazardous pollutants (Bell et al, 2004 ; Borhani et al, 2022a , 2022b , 2022c ; Ghahremanloo et al, 2021 ; Pierrehumbert, 2014 ; Stohl et al, 2015 ). Tropospheric ozone (O 3 ) concentrations are mostly controlled by the photochemical-oxidant precursors, such as nitrogen monoxide (NO), nitrogen dioxides (NO 2 ), carbon monoxide (CO), and also solar radiation and temperature (Cooper et al, 2012 ; Frost et al, 2006 ).…”

Section: Introductionmentioning

confidence: 99%

Current Status and Future Forecast of Short-lived Climate-Forced Ozone in Tehran, Iran, derived from Ground-Based and Satellite Observations

Borhani

Motlagh

Ehsani

et al. 2023

Water Air Soil Pollut

Self Cite

View full text Add to dashboard Cite

“…With the rapid development of the world population, economy, and industrialization, energy consumption also grows increasingly. Air pollution has become an urgent global health problem ( 1 , 2 ). Particulate matter 2.5 (particulate matter with an aerodynamic diameter of ≤ 2.5 µm, PM 2.5 ), as one of the main pollutants, can penetrate the respiratory barrier simply with its extremely tiny particle diameter by absorbing and combining with toxic compounds ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

PM2.5 induced liver lipid metabolic disorders in C57BL/6J mice

Zhang,

Ma,

Liu

et al. 2023

Front. Endocrinol.

View full text Add to dashboard Cite

PM2.5 can cause adverse health effects via several pathways, such as inducing pulmonary and systemic inflammation, penetration into circulation, and activation of the autonomic nervous system. In particular, the impact of PM2.5 exposure on the liver, which plays an important role in metabolism and detoxification to maintain internal environment homeostasis, is getting more attention in recent years. In the present study, C57BL/6J mice were randomly assigned and treated with PM2.5 suspension and PBS solution for 8 weeks. Then, hepatic tissue was prepared and identified by metabolomics analysis and transcriptomics analysis. PM2.5 exposure can cause extensive metabolic disturbances, particularly in lipid and amino acids metabolic dysregulation.128 differential expression metabolites (DEMs) and 502 differently expressed genes (DEGs) between the PM2.5 exposure group and control group were detected. The Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses showed that DEGs were significantly enriched in two disease pathways, non-alcoholic fatty liver disease (NAFLD) and type II diabetes mellitus (T2DM), and three signaling pathways, which are TGF-beta signaling, AMPK signaling, and mTOR signaling. Besides, further detection of acylcarnitine levels revealed accumulation in liver tissue, which caused restricted lipid consumption. Furthermore, lipid droplet accumulation in the liver was confirmed by Oil Red O staining, suggesting hepatic steatosis. Moreover, the aberrant expression of three key transcription factors revealed the potential regulatory effects in lipid metabolic disorders, the peroxisomal proliferative agent-activated receptors (PPARs) including PPARα and PPARγ is inhibited, and the activated sterol regulator-binding protein 1 (SREBP1) is overexpressed. Our results provide a novel molecular and genetic basis for a better understanding of the mechanisms of PM2.5 exposure-induced hepatic metabolic diseases, especially in lipid metabolism.

show abstract

Evaluation of short-lived atmospheric fine particles in Tehran, Iran

Cited by 13 publications

References 54 publications

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Current Status and Future Forecast of Short-lived Climate-Forced Ozone in Tehran, Iran, derived from Ground-Based and Satellite Observations

PM2.5 induced liver lipid metabolic disorders in C57BL/6J mice

Contact Info

Product

Resources

About

Evaluation of short-lived atmospheric fine particles in Tehran, Iran

Cited by 13 publications

References 54 publications

Variations of PM2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Variations of PM2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Current Status and Future Forecast of Short-lived Climate-Forced Ozone in Tehran, Iran, derived from Ground-Based and Satellite Observations

PM2.5 induced liver lipid metabolic disorders in C57BL/6J mice

Contact Info

Product

Resources

About

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018

Variations of PM_2.5 and Health Risk Assessment in the City of Mashhad During 2010-2018