Evaluation of short term neurological outcomes in children diagnosed with brain abscesses

Acar, Manolya; Sütçü, Murat; Aktürk, Hacer; Muradova, Aygozel; Törün, Selda Hançerli; Salman, Nuran; Çalışkan, Mine; İzgi, Nail; Somer, Ayper

doi:10.5137/1019-5149.jtn.18672-16.1

Cited by 11 publications

(6 citation statements)

References 20 publications

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“…The most common presenting signs and symptoms are fever, headache, vomiting, and focal neurologic deficits. 12,13 Conservative treatment with parenteral antibiotics alone has become more common 13,25 The 3 toddlers in this study with intracranial abscesses or infected cysts presented with fever and vomiting. One was successfully treated nonsurgically.…”

Section: Discussionmentioning

confidence: 88%

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Clinical Presentation of Toddlers With New Intracranial Space-Occupying Lesions

Khan

Azadian²,

Richter³

et al. 2021

Pediatr Emer Care

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Intracranial space occupying lesions (ICSOLs) like tumors and abscesses can be life-threatening conditions. It can be especially difficult to diagnose these conditions in toddlers. We aimed to describe symptoms and signs present in a sample of toddlers with ICSOLs.Methods: We performed a retrospective chart review of 15 toddlers with intracranial tumors, abscesses, or infected cysts. We collected data on the presence of various signs and symptoms on presentation to the emergency department.Results: Eight toddlers (53%) presented with vomiting. A change in behavior was the second most common symptom (6, 40%). Seven children (47%) had motor weakness, and 5 (33%) had ataxia. Eleven of the 12 children with tumors (92%) had documented abnormal neurologic signs on initial physical examination.Conclusions: Vomiting, a change in behavior, and an abnormal neurologic examination were common signs and symptoms in our sample of toddlers with ICSOLs. An accurate history and appropriate neurologic examination can help physicians make this challenging diagnosis in this age group.

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Section: Discussionmentioning

confidence: 88%

“…Ten (67%) of the subjects were girls. The median respiratory rate was 20 (IQR, [18][19][20][21][22][23][24][25][26]; heart rate, 113 (IQR, 94-124); systolic blood pressure, 100 (IQR, 96-109); and diastolic blood pressure, 61 (IQR, 55-67).…”

Section: Resultsmentioning

confidence: 99%

Clinical Presentation of Toddlers With New Intracranial Space-Occupying Lesions

Khan

Azadian²,

Richter³

et al. 2021

Pediatr Emer Care

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“…To date, 23 cases of that entity were described in world literature, and we present the 24th pediatric patient. The mean age of occurrence in cerebral abscesses ranges between 4 and 7 years [28]. Considering brainstem abscesses, the mean age of occurrence during childhood was 6.4 years, ranging from 7 months to 16 years.…”

Section: Historical Backgroundmentioning

confidence: 99%

“…Clinical presentation varies depending on abscess location in the brain. In up to 35% of patients, the primary source of infection cannot be determined; therefore, they are classified as cryptogenic [4,28,29]. Streptococci and Staphylococci are the most frequently isolated microorganisms, followed by anaerobes and Gramnegative enteric bacteria [30,31].…”

Section: Introductionmentioning

confidence: 99%

Clinical features, microbiology, and management of pediatric brainstem abscess

2020

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Purpose Brainstem abscess is a rare condition accounting for merely 1% of brain abscesses incidence in the pediatric population. This study aimed to present a single patient with a pontine abscess and review the literature to highlight clinical features, diagnosis, and management of brainstem abscess. Methods The PubMed database was screened for English-language articles concerning pediatric brainstem abscess. We, therefore, identified 22 publications, which concisely depict 23 cases. Our study reports on the 24th pediatric patient diagnosed with that entity. All included reports were analyzed in terms of clinical presentation, diagnosis, management, and outcomes of described patients. Results There was slight women predominance (15:9), with a mean age of occurrence 6.4 years, ranging from 7 months to 16 years. Pons was the most common location of brainstem abscess, occurring in 75% of patients. Clinically, they mostly presented with cranial nerves palsy (79.2%), hemiparesis (66.7%), and pyramidal signs (45.8%). The classic triad of symptoms, including fever, headache, and the focal neurologic deficit was present in 20.8% of patients. Positive pus cultures were obtained in 61.1%. Streptococci and Staphylococci were the most frequently identified pus microorganisms. Outcomes were satisfactory, with a 79.2% rate of general improvement. Conclusions Neurosurgical aspiration is a safe and beneficial therapeutic method. It should always be considered and should promptly be performed when the conservative treatment is not successful and clinical deterioration occurs. Prognosis in pediatric brainstem abscess is generally favorable. Most patients recover with minor neurologic deficits or improve completely.

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“…4 Only 28% of cases demonstrated in classic triad of focal neurological signs, fever and headache. 5 Before the time of computerized tomography and when imaging techniques are not available early diagnosis and treatment usually delayed. But with the development of microbiological laboratories it is not difficult to detect anaerobic bacteria.…”

Section: Introductionmentioning

confidence: 99%

Incidence and Predisposing factors of Brain Abscess in Children at a Tertiary Care Center Dera Ghazi Khan

Bokhari

Qureshi

2021

Pak J Neurol Surg

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Objective: A cross sectional study was aimed to investigate the incidence and predisposing factors of brain abscess in children. Material and Methods: The study was conducted in the departments of Neurosurgery and Pediatric Surgery, Ghazi Khan Medical College and Hospital DG khan. Thirty two children with brain abscess were enrolled in the study. A diagnosis of brain abscess was made on clinical and radiological basis. T-test and chi square were applied to see the association between variables. Results: Most common location of Abscess was found as frontal in 21.9% patients, temporo parietal in 53.1% patients and occipital in 25.0% patients. Streptococci was the most common microorganism on culture reported, noted in 46.9% patients. Major predisposing factors (p = 0.000) and location of abscess (p = 0.003) were the effect modifiers for microorganism on culture reports. Conclusion: Streptococci was the most common abscess causing microorganism causing about 47% of total abscess causing pathogens. Main predisposing factors were: otitis media, cyanotic heart disease and post head injury otorrhea. Keywords: Brain abscess; Children; Otogenic brain abscess; Otitis media, Seizures; Streptococci.

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Evaluation of short term neurological outcomes in children diagnosed with brain abscesses

Cited by 11 publications

References 20 publications

Clinical Presentation of Toddlers With New Intracranial Space-Occupying Lesions

Clinical Presentation of Toddlers With New Intracranial Space-Occupying Lesions

Clinical features, microbiology, and management of pediatric brainstem abscess

Incidence and Predisposing factors of Brain Abscess in Children at a Tertiary Care Center Dera Ghazi Khan

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