Evaluation of some pharmacological activities of Eugenia uniflora L.

Schapoval, Elfrides E.S.; Silveira, Silvia Maria; Miranda, Mayker Lázaro Dantas; Alice, C.B.; Henriques, Amélia T.

doi:10.1016/0378-8741(94)01178-8

Cited by 117 publications

(73 citation statements)

References 13 publications

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“…Regarding the extracts from E. uniflora, the differences among antifungal assay procedures as well as the extraction parameters such as the solvent (aqueous or hydroalcoholic mixtures) and/or extraction procedures (infusion, decoction or maceration) may explain the better antifungal performance found in this study, in comparison with previous studies (Schapoval et al, 1994;Holetz et al, 2002). As well know, the extractive conditions (procedure e solvents) plays an important role on the extract chemical spectrums, in special the polyphenolic compounds from leaves of E. uniflora such as hydrolysable tannins (Lee et al, 1997(Lee et al, , 2000 and/or quercetin/ myricetin-glicosyl derivates (Rattman et al, 2012).…”

Section: Discussioncontrasting

confidence: 56%

Antifungal activity of medicinal plants from Northeastern Brazil

Ferreira¹,

Santiago²,

Langassner³

et al. 2013

J. Med. Plants Res.

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The aim of this work was to find how medicinal plants play an important role as source of new bioactive molecules. To evaluate the antifungal activity of 10 medicinal plants from northeastern Brazil, traditionally used as anti-infective agents. The activity of 30 crude extracts (water; ethanol:water, 1:1; acetone:water, 1:1) against four standard species of Candida yeasts (Candida albicans ATCC 90028, Candida dubliniensis ATCC 7289, Candida glabrata ATCC 2001 and Candida krusei ATCC 6258) was investigated by the Minimal Inhibitory Concentration (MIC), using the microdilution method and the working range used was from 1.95 to 1000 μg/mL. Extracts from leaves of Eugenia uniflora (Myrtaceae), stem bark of Caesalpinia ferrea (Caesalpinaceae) and leaves of Psidium guajava (Myrtaceae) showed significant activity against all yeasts evaluated. The best antifungal activities were achieved against C. glabrata and C. krusei by E. uniflora extract (MIC = 15.62) and followed by extracts from C. ferrea and P. guajava (MIC ranged from 15.62 to 250 µg/mL). E. uniflora also showed fungicidal properties against all yeasts, especially against Candida dubliniensis. This study identified plant species that may be candidates for the development of alternative treatments for candidiasis.

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Section: Discussioncontrasting

confidence: 56%

Antifungal activity of medicinal plants from Northeastern Brazil

Ferreira¹,

Santiago²,

Langassner³

et al. 2013

J. Med. Plants Res.

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“…The leaves of several species from this family have been used in folk medicine for their interesting bioactivities, such as antidiarrhetic, antibacterial, vermifuge and anti-inflammatory properties. These activities have been related to the presence of tannins and terpenoids (Schapoval et al, 1994;Slowing et al, 1994;Apel et al, 2002;Kim et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Anti-inflammatory activity of essential oil from leaves ofMyrciaria tenellaandCalycorectes sellowianus

Apel

Lima

Sobral

et al. 2010

Pharmaceutical Biology

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“…Therefore, this study established that E. uniflora leaf extract has larvicidal effects on A. aegyptii. Since the plant is non-toxic (Schapoval et al, 1994), purified fractions (D 1 or D 3 ) should be considered for commercial exploitation as a cheaper and alternative larvicide in the control of dengue and yellow fever diseases, especially among the rural populations of Africa. …”

Section: Resultsmentioning

confidence: 99%

“…Insecticidal activity of its leaf volatile oil (Gbolade and Adebayo, 1993) and larvicidal activity of the extract (Omena et al, 2005) have been reported. Since the E. uniflora leaf extract has been reported to be non-toxic (Schapoval et al, 1994), its larvicidal activity against A. aegyptii was investigated.…”

Section: Introductionmentioning

confidence: 99%

Larvicidal properties of Eugenia uniflora leaves

Famuyiwa¹,

Adebajo²

2012

ABJNA

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Eugenia uniflora is used ethnomedicinally in Nigeria for diseases including malaria and in Brazil the leaves are spread on the floor for its insect-repellent activity. Search for plants useful in the control of vector of Dengue fever, necessitated investigation of the activity of E. uniflora leaf against fourth instars larvae of Aedes aegyptii, using bioactivity guided fractionation. Larvicidal activity (LC 50 2.74 and 2.18 mg/ml at 24 and 48 h) of the leaf methanolic extract, comparable (p > 0.05) to Endosulphan (LC 50 0.93 and 0.90 mg/ml at 24 and 48 h), was concentrated in the nhexane partition fraction (LC 50 2.58 and 1.87 mg/ml at 24 and 48 h). Vacuum liquid chromatography of n-hexane fraction gave fifth and sixth bulked fractions with significantly (p < 0.05) higher larvicidal activities. Column chromatography of these combined fractions yielded first and third subfractions with LC 50 1.01 and 1.17 mg/ml at 24 h, respectively and activities that were similar (p > 0.05) to that of Endosulphan and better than their mother fractions. The results established the larvicidal activity of E. uniflora leaf and encouraged further development of these fractions as alternative larvicide in the control of Dengue fever, especially among the rural populations of Africa.

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Evaluation of some pharmacological activities of Eugenia uniflora L.

Cited by 117 publications

References 13 publications

Antifungal activity of medicinal plants from Northeastern Brazil

Antifungal activity of medicinal plants from Northeastern Brazil

Anti-inflammatory activity of essential oil from leaves ofMyrciaria tenellaandCalycorectes sellowianus

Larvicidal properties of Eugenia uniflora leaves

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