Background Dental impressions should be disinfected to stop the transmission of germs among dental workers since they provide a risk of diseases. The aim of this study was to examine the effects of two disinfectants (16 mg/ml propolis and 5.25% sodium hypochlorite) on the detail reproduction, linear dimensional change, compatibility with gypsum products, wettability, and surface roughness of addition silicon material. Methods Ninety specimens were created using Addition silicon impression material, and they were then divided into three groups at random. Ten specimens from each test group were used in each test. Utilizing apparatus made in accordance with ISO 4823:2015, detail reproduction, linear dimensional change, and compatibility with gypsum products are assessed. A digital Profilometer was uutilized to evaluate surface roughness, and a Goniometer was utilized to evaluate wettability by taking the contact angle. Before testing, the specimens were immersed for 10 minutes each in two disinfection solutions: 16 mg/ml propolis and 5.25% NaOCL. The control group received no disinfection. One-way ANOVA tests and the Kruskal-Wallis test, which was statistically significant at a level of p 0.05, were used to examine the data. Results Comparing the linear dimensional change, surface roughness, and wettability of Addition silicon specimens immersed in 16 mg/ml propolis, 5.25% NaOCL, or the control group demonstrated statistically significant differences (p< 0.05), while details reproduction and compatibility with gypsum revealed statistically no significant differences (p > 0.05). Conclusion Within the parameters of this study, the addition silicon can be immersed in 16 mg/ml propolis for 10 min. to disinfect it without compromising its dimensional accuracy, detail reproduction, compatibility with gypsum products, surface roughness, or wettability.