Evaluation of suspected interferents for TNT detection by ion mobility spectrometry

Matz, Laura M.; Tornatore, Pete; Hill, Herbert H.

doi:10.1016/s0039-9140(00)00663-9

Cited by 73 publications

(40 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…IMS is a well-known method to analyze chemical substance using gas-phase mobility in a weak electric field [14][15][16], and is more and more used in the detection of explosives, drugs, chemical warfare agents, biological and medical samples [17][18][19][20][21][22][23][24][25]. Unlike the mass spectrometry [26,27], which operates in vacuum, IMS detects chemical compounds at atmospheric pressure.…”

Section: Introductionmentioning

confidence: 99%

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Han

Cheng

et al. 2012

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Han

Cheng

et al. 2012

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

“…This is successful due to its high sensitivity, portability and rapid analysis but specificity can be an issue. [23] There are known molecules within the forensics community that have similar mobility spectra to molecules of interest, which can cause false positives. MS is advantageous as it combines high sensitivity and rapid analysis with excellent specificity.…”

Section: Chemical Forensics For National Security Trace Detection Of mentioning

confidence: 99%

Ambient mass spectrometry: advances and applications in forensics

Green

Salter

Stokes³

et al. 2009

Surface & Interface Analysis

View full text Add to dashboard Cite

Ambient mass spectrometry (ambient MS) is a powerful and rapidly growing new field that provides high sensitivity MS directly from surfaces at ambient pressure. There is now a rich evidence base in the published literature of the success of these methods for forensic analysis including: detection of explosives at nanogram levels; chemical composition of counterfeit pharmaceutical tablets, detection of drugs of abuse from biological liquids such as urine and plasma; breath analysis of metabolites; and imaging analysis for document verification and fingerprint identification. Recent developments in miniaturised (shoe-box sized) mass spectrometers have enabled these developments to be translated to portable on-scene detection and first responder usage. In this review, we illustrate and compare the effectiveness of the most popular and promising techniques of desorption electrospray ionisation (DESI), direct analysis in real time (DART), plasma assisted desorption ionisation (PADI) and extractive electrospray ionisation (EESI). Forensic analysis by its very definition must stand up to scrutiny in a court of law. It is therefore essential that measurements are repeatable, valid, traceable and fit for purpose. The establishment of a measurement infrastructure is therefore essential to ensure that the methods used may be accredited and conform to relevant quality systems and procedures.

show abstract

“…1a feature the presence of a prominent artifact with a drift time of 16.2 ms. Subsequent experiments that spiked TNT on a filter region devoid of polymer were unable to detect TNT, indicating that the lack of signal for TNT resulted from competitive ionization [15,16]. An H 2 (dihed) ligand standard gave a signal with a longer drift time (~20.9 ms) than the artifact.…”

Section: Filter Backgroundsmentioning

confidence: 99%

Selective sampling with direct ion mobility spectrometric detection for explosives analysis

Harvey

Ewing

Waltman

2009

Int. J. Ion Mobil. Spec.

View full text Add to dashboard Cite

This study investigates the potential and limitations of a field-deployable analytical approach that involves selective capture of explosive materials with direct analysis by ion mobility spectrometry (IMS). Selective capture of explosives was performed on deactivated quartz fiber filters impregnated with metal β-diketonate polymers. These Lewis acidic polymers selectively interact with Lewis base analytes such as explosives. The filters were directly inserted into an IMS instrument for analysis. The uptake kinetics of 2,4,6-trinitrotoluene (TNT) from a saturated atmosphere were characterized, and based on these studies, passive equilibrium sampling was applied to estimate the TNT concentration within an ammunition magazine that contained bulk TNT. Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) uptake from a saturated environment also was examined over a one-month period. Each incremental sampling period showed increasing quantities of RDX culminating with collection of approximately 5 ng of RDX on the filter at the end of one month. This is the first time that gas-phase uptake of RDX has been demonstrated.

show abstract

Evaluation of suspected interferents for TNT detection by ion mobility spectrometry

Cited by 73 publications

References 24 publications

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Ambient mass spectrometry: advances and applications in forensics

Selective sampling with direct ion mobility spectrometric detection for explosives analysis

Contact Info

Product

Resources

About