Evaluation of the Accuracy of the CyberKnife

Jang, Jisun; Kang, Yun Ju; Choi, Byung Ock; Choi, Inyoung; Kim, Moon Chan; Shin, Dong Oh; Shin, Dongho; Cho, Kwang Hwan; Min, Chul Kee; Kwon, Soo Il

doi:10.1007/978-3-540-36841-0_508

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…The software analyzed the ROI bony markers and the 6-D error of patient posture. The manipulator automatically corrected the position and orientation to compensate for the positioning error [ 6 ]. Dose fractionation and dosage per session were developed based on the patient’s general condition, performance status, tumor size, and location.…”

Section: Methodsmentioning

confidence: 99%

“…Stereotactic radiotherapy allows tumor treatment with high dosage and low fractionation, thereby overcoming the dosage limitations of conventional radiation therapy and improving local control rate [ 1 - 5 ]. CyberKnife (CK) is one type of stereotactic radiosurgery system, employing real-time image guidance and a synchronized respiratory tracking system to deliver high dosages of hypofractionated radiation dynamically to the tumor with spatial precision that can reach the sub-millimeter scale [ 6 ]. Due to improved conformation and precision, a lethal dose of radiation can be delivered to the tumor while the surrounding normal tissues or vital organs are radiated with lower dosages and exposure ranges, leading to fewer side effects and improved safety.…”

Section: Introductionmentioning

confidence: 99%

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Treating Adrenal Tumors in 26 Patients with CyberKnife: A Mono-Institutional Experience

Li¹,

Shi

Wang³

et al. 2013

PLoS ONE

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BackgroundCyberKnife (CK) is a novel stereotactic radiosurgery system for treating tumors in any part of the body. It is a non-invasive or minimally invasive tumor treatment modality that can deliver high doses of spatially precise radiation and minimize exposure to neighboring healthy tissues or vital organs. The purpose of this study was to investigate the safety and efficacy of CK in the treatment of adrenal tumors. Methods and ResultsWe performed a retrospective analysis of 26 patients with adrenal tumors who had been treated with CK in the radiotherapy center of our hospital between March 2009 and March 2012. Eight patients had primary adrenal tumors and 18 patients had metastatic adrenal tumors. In addition to CK, 4 patients received chemotherapy and 2 patients received immunotherapy. The average tumor volume was 72.1 cm3 and the prescribed radiation dosage ranged from 30 to 50 Gy and was fractionated 3 to 5 times with a 58% to 80% isodose line. Abdominal CT was performed between 1 to 3 months after the CK treatment to evaluate the short-term efficacy with follow-up examinations once every 3 months. Three patients had complete remission, 12 patients had partial remission, 5 patients had stable disease, and 6 patients had progressive illness. The effective rate of pain relief was 93.8% and the disease control rate was 77% with a median overall survival of 17 months and a median progression-free survival of 14 months. Treatment Related toxicity was well-tolerated, but preventative measure need to be taken for radiation enteritis.Conclusions CK is safe and effective for treating adrenal tumors with few adverse reactions. Nonetheless, its long-term effects requires further follow-up.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Treating Adrenal Tumors in 26 Patients with CyberKnife: A Mono-Institutional Experience

Li¹,

Shi

Wang³

et al. 2013

PLoS ONE

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“…This system, used without a frame, allows for treatment targets either inside or outside the brain. The accuracy of the Cyberknife system, however, is only in the range of 0.93 mm [28]. The largest reported Cyberknife experience for glomus tumours was on 11 patients [29] where 18% of cases demonstrated tumour size reduction and no permanent complications were reported.…”

Section: Radiosurgical Seriesmentioning

confidence: 95%

Successful treatment of glomus jugulare tumours with gamma knife radiosurgery: clinical and physical aspects of management and review of the literature

et al. 2010

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“…However, this approach introduces the generic limitations of a human operator (such as physiological latency), and even for these systems, the intrinsic accuracy of the components has significant effect on performance. (Kwoh et al, 1988); 2 (Paul et al, 1992); 3 (Taylor, 2001); 4 (Nishihara et al, 2006); 5 (Li et al, 2002); 6 (Varma et al, 2006); 7 (Haidegger et al, 2008);8 (Kwartowitz et al, 2006); 9 (Kwartowitz et al, 2007);10 (Dieterich et al, 2003); 11 (Jang et al, 2006); 12,13 (Cleary et al, 2006); 14 (Lieberman et al, 2006).…”

Section: Examples Of Accuracy Measurementsmentioning

confidence: 99%

From Concept to Market

Haidegger

Rudas

2015

Advances in Computational Intelligence and Robotics

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Surgical robotics and supporting technologies have really become a prime example of modern applied information technology infiltrating our everyday lives. The development of these systems spans across four decades, and only the last few years brought the market value and saw the rising customer base imagined already by the early developers. This chapter guides the reader through the historical development of the most important systems and provides references and lessons learnt for current engineers facing similar challenges. A special emphasis is put on system validation, assessment, and clearance, as the most commonly cited barrier hindering the wider deployment of a system.

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Evaluation of the Accuracy of the CyberKnife

Cited by 3 publications

References 19 publications

Treating Adrenal Tumors in 26 Patients with CyberKnife: A Mono-Institutional Experience

Treating Adrenal Tumors in 26 Patients with CyberKnife: A Mono-Institutional Experience

Successful treatment of glomus jugulare tumours with gamma knife radiosurgery: clinical and physical aspects of management and review of the literature

From Concept to Market

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