Evaluation of The Antibiotic Use for Surgical Prophylaxis in Paediatric Acute Appendicitis

Sviestiņa, Inese; Mozgis, Dzintars

doi:10.5530/jyp.2015.1.3

Cited by 5 publications

(8 citation statements)

References 23 publications

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“…respectively cefotaxim 51.5% and ceftriaxone 13.39% was most commonly prescribed drug. 15 In our study mean age of the patient was 36.64±15.9 years (Mean±SD) and the range of ages was between 18-90 years old which is differ from study conducted by Tourmousoglou CE et al, at Department of Pharmacology, Medical School, University of Athens, Athens, Greece found that mean age of the population was 58.8+15.2 years. 16 In our study, the 39% of patients received antibiotic combination (two or more antibiotic) and 18% of patient received monotherapy of antibiotic.…”

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confidence: 89%

Evaluation of prescription pattern of antibiotics for surgical prophylaxis in secondary care hospital

Joshi¹,

Rizwan²,

Kothiyal³

et al. 2017

Int J Basic Clin Pharmacol

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Background: Antibiotic prophylaxis is the prevention and in incidence of surgical site infection. This study evaluates the rational use of antibiotics prophylaxis prior to surgery amongst hospitalized patients. Objectives of the study were to investigate the utilization and evaluation pattern of antibiotics for surgical prophylaxis in surgery department.Methods: A prospective observational study was conducted on 100 patients receiving antibiotics in the Department of Surgery of Brijesh Hospital Ramnagar (Nainital) Uttarakhand. Patient undergoing antibiotic prophylaxis treatment were included in the study, exclusion of those patients who had age less than 18, patients with psychiatric disease and those patients not willing to sign on inform consent form.Results: The result observed in 100 patients follow up 8 weeks and evaluate the appropriate use of prophylaxis of antibiotics majority of patients were age group 18-30 years, followed by 41-50 years, 51-60 years, majority were reported in female patients than male, higher utilization of cephalosporins were commonly prescribed due to their relatively lower toxicity and broader spectrum activity and broader coverage of organism for several serious gram negative infection 30 (30%) patients were prescribed penicillin with aminoglycosides, 10 (10%) patients were prescribed with nitroimidazole antibiotics.Conclusions: The overall scenario of antibiotic usage in a Hospital was as per standard recommendations and all the antibiotics used were according to their standard adult and titrated doses and frequencies. In this study we found that Cephalosporines, Penicillins, Aminoglycosides and Nitroimidazole were mostly used classes of drug. Adverse Drug Reactions were minor and well managed.

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contrasting

confidence: 89%

Evaluation of prescription pattern of antibiotics for surgical prophylaxis in secondary care hospital

Joshi¹,

Rizwan²,

Kothiyal³

et al. 2017

Int J Basic Clin Pharmacol

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“…19 The improper and unnecessary use of antibiotics are widely practiced athospital setting, may include inadequate dose, unnecessary prolonged surgical prophylaxis. 20,21 This is one of the study from developing country that describes (12) 19 (13) 6 (4) Evidence based prescriptions 11 (12) 8 (21) 3 (8) 0 (0) no. of unnecessary use of antibiotics…”

Section: Discussionmentioning

confidence: 99%

A Study of Unnecessary Use of Antibiotics at a Tertiary care hospital: Urgent need to implement antimicrobial stewardship programs

Bin¹,

Arshad²,

Junaid³

et al. 2015

JYP

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Background:The resistant bacteria are on upward trend in the third world countries especially in Pakistan. One of the reasons is injudicious prescription of antibiotics. The aim of this study was to estimate the unnecessary use of antibiotics at a tertiary care hospital at Lahore Pakistan. Methods and Material: This is the descriptive, retrospective observational study. A total of 104 persons were recruited from an inpatient department of surgery, medicine and gynaecology in a tertiary care hospital were observed and data collected from June 2014 to July 2014 on the daily basis. The dose and the route of given antibiotics were observed in addition to their baseline tests like CBC (Complete Blood Count), urine complete examination, especially with respect to TLC (Total Leucocyte Count) and pus cells, and if any cultures were done along. Descriptive statistics was applied to data to inference results. Results: A total of 104 persons, consisting of 41% male and 59% female were included in the study. The mean age of total patients were 43.97± 18.3 years. 9.61% patients were not receiving antibiotics. 90% patients received 143(100%) antimicrobials during the period of study with a range of 1-3 antimicrobials per patient. 30% antimicrobials were prescribed unnecessarily without any clinical evidence of infection. The most common prescribed antibiotic was ceftriaxone 30%. It was 88% of the prescription that were prescribed without ordering the culture test. 83 prescriptions were empiric, containing 29% of the unnecessary antibiotics. The unnecessarily prescribed antimicrobials cost 32,865 PKR per day to the sample population. Conclusion: Antimicrobials are being used unnecessarily, even empirical treatment are without significant sound clinical evidence. The antimicrobial resistance and emergence of new mutant strains can be attributable to injudicious use of antibiotics. Antimicrobial stewardship programs should be used to minimize this problem.

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“…Uno de los mayores logros tras la implantación de nuestro plan fue la mejoría del cumplimiento del protocolo de profilaxis antibiótica, que pasó del 69.2 al 96.2% (p < 0.001), con una adecuación global del 81.9%, considerando una administración correcta si se cumplían todos los criterios (elección del antibiótico, dosis, tiempo de inicio, vía de administración y duración). Estas cifras son superiores a las de otros trabajos nacionales e internacionales revisados 7,22,[33][34][35] . La causa de inadecuación más frecuente fue no administrar la profilaxis en el momento previo a la cirugía definido en el protocolo.…”

Section: Discussionunclassified

Efecto de un Plan de Mejora de Calidad y Seguridad Clínica en la incidencia de infección de sitio quirúrgico en apendicectomía. Estudio cuasi-experimental

Del-Moral-Luque¹,

Sánchez-Santana²,

Gil-Yonte³

et al. 2018

CIRU

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Evaluation of The Antibiotic Use for Surgical Prophylaxis in Paediatric Acute Appendicitis

Cited by 5 publications

References 23 publications

Evaluation of prescription pattern of antibiotics for surgical prophylaxis in secondary care hospital

Evaluation of prescription pattern of antibiotics for surgical prophylaxis in secondary care hospital

A Study of Unnecessary Use of Antibiotics at a Tertiary care hospital: Urgent need to implement antimicrobial stewardship programs

Efecto de un Plan de Mejora de Calidad y Seguridad Clínica en la incidencia de infección de sitio quirúrgico en apendicectomía. Estudio cuasi-experimental

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