Evaluation of the biocompatibility of resin-based root canal sealers in rat periapical tissue

Mutoh, Noriko; Satoh, Takenori; Watabe, Hirotaka; Tani‐Ishii, Nobuyuki

doi:10.4012/dmj.2012-218

Cited by 14 publications

(7 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The physical structure and surface characteristics of the material associated to its cytotoxicity are probably related to biocompatibility [32]. The results presented in this study are very likely to explain why AH Plus is considered a good biocompatible material [33] and also enforce the morphological behavior of human periodontal ligament fibroblasts on MTA-based cements [31]. …”

Section: Discussionmentioning

confidence: 98%

Physicochemical Properties and Surfaces Morphologies Evaluation of MTA FillApex and AH Plus

Borges

Dorileo

Villa

et al. 2014

The Scientific World Journal

View full text Add to dashboard Cite

The solubility, pH, electrical conductivity, and radiopacity of AH Plus and MTA FillApex were evaluated. In addition, the surfaces morphologies of the sealers were analyzed by using scanning electron microscopy. For pH test, the samples were immersed in distilled water at different periods of time. The same solution was used for electrical conductivity measurement. The solubility and radiopacity were evaluated according to ANSI/ADA. Statistical analyses were carried out at 5% level of significance. MTA FillApex presented higher mean value for solubility and electrical conductivity. No significant difference was observed in the mean values for pH reading. AH Plus presented higher radiopacity mean values. MTA FillApex presented an external surface with porosities and a wide range of sizes. In conclusion, the materials fulfill the ANSI/ADA requirements when considering the radiopacity and solubility. AH Plus revealed a compact and homogeneous surface with more regular aspects and equal particle sizes.

show abstract

Section: Discussionmentioning

confidence: 98%

Physicochemical Properties and Surfaces Morphologies Evaluation of MTA FillApex and AH Plus

Borges

Dorileo

Villa

et al. 2014

The Scientific World Journal

View full text Add to dashboard Cite

show abstract

“…AH Plus is an epoxy resin‐based endodontic sealer recommended by several researchers because it has biological, physical, and chemical superiorities among all sealers (Mutoh et al ., ; Üstün et al ., ; Asheibi et al ., ). During root canal obturation, uncured AH Plus residues may remain on access cavity walls, especially over the dentinal surface, due to its anatomically complex structure (Kuga et al ., ).…”

Section: Discussionmentioning

confidence: 99%

The bond strength of adhesive resins to AH plus contaminated dentin cleaned by various gutta-percha solvents

et al. 2015

View full text Add to dashboard Cite

The optimal bonding of adhesives to dentin requires the sealer to be completely removed from dentinal walls. The aim of this study was to investigate the effect of different cleaning procedures using gutta-percha solvents on bond strength of adhesive resins to AH Plus contaminated dentin (APCD). The pulp chamber dentin surfaces were contaminated with AH Plus and cleaned with five different techniques (dry cotton, chloroform, orange oil, eucalyptol, and ethanol). Then, Clearfil SE Bond (CSE) (Kuraray), and Tetric N Bond (TNB) (Ivoclar Vivadent) were applied and filled with a composite resin. The serial sticks (1 × 1 mm) were obtained and tested for microtensile bond strength. Scanning electron microscopy (SEM) was used for analysis of debonded surfaces. Ethanol exhibited the highest bond strength to APCD followed by dry cotton. There was no statistically significant difference between ethanol and dry cotton (p > 0.05). Eucalyptol showed the lowest bond strength to APCD and statistically significant differences (p < 0.05) in comparison with other groups. APCD reduced the bond strength of all adhesive resins. Dry cotton, ethanol, and chloroform were the most suitable techniques when used with CSE together, whereas ethanol was best with TNB.

show abstract

“…High levels of inflammation have also been detected in periapical and subcutaneous tissues after the use of epoxy resin-based sealers 198,213) . In a rat model study, AH Plus induced milder inflammatory response than a ZOE sealer in the periapical tissue 214) .…”

Section: Antimicrobial Activitymentioning

confidence: 90%

Comprehensive review of current endodontic sealers

et al. 2020

View full text Add to dashboard Cite

Choosing an endodontic sealer for clinical use is a decision that contributes to the long-term success of non-surgical root canal treatment (NSRCT) 1) . Sealers are used as a thin tacky paste which functions as a lubricant and luting agent during obturation, allowing the core obturation material, such as gutta-percha points or other rigid materials, to slide in and become fixed in the canal 2,3) . Sealers can fill voids 4) , lateral canals 5) , and accessory canals where core obturation materials cannot infiltrate 6,7) . If the sealer does not perform its function, microleakage may cause NSRCT failure via clinically undetectable passage of bacteria, fluids, molecules or ions between the tooth and restorative material 8,9) . Knowing the qualities and characteristics of an endodontic sealer is critical to determining the best selection and application for each clinical case.Endodontic sealers are categorized by composition based on setting reaction and composition: zinc oxideeugenol, salicylate, fatty acid, glass ionomer, silicone, epoxy resin, tricalcium silicate, and methacrylate resin sealer systems (Table 1). Some novel sealers contain fillers or ceramic powders including calcium hydroxide, mineral trioxide aggregate (MTA), and calcium phosphate; however, they are fundamentally composed of the above sealer matrices. Until recently, many review articles were published within sealer types [10][11][12][13][14][15][16] . However, few reviews have been published that cover all sealer types 17,18) . Therefore, in this comprehensive review, a historical perspective of each sealer type will be discussed first, followed by a description of the properties of all sealer types, such as setting time and solubility, sealing ability, antimicrobial activity, and biocompatibility and cytotoxicity. Sealer attributes such as the rheology 19) , radiopacity 20) , and tooth discoloration [21][22][23] have been shown to be satisfactory and will not be discussed in detail. CURRENT ROOT CANAL SEALERS AND HISTORY Chelate formationMany dental luting agents set by way of a chelation reaction, the formation of metal complexes with polydentate (usually organic) ligands 24) . Two of the most common chelates used in dentistry are eugenolates and salicylates. For eugenolates, the setting reaction starts with water that hydrolyzes the zinc oxide to form zinc hydroxide. The zinc hydroxide and eugenol chelate and solidify 25) . For salicylates, the ion is calcium, usually formulated using calcium oxide. Although uncommon, fatty acids have also been used as ligands for chelate sealers, in conjunction with zinc oxide.

show abstract

Evaluation of the biocompatibility of resin-based root canal sealers in rat periapical tissue

Cited by 14 publications

References 35 publications

Physicochemical Properties and Surfaces Morphologies Evaluation of MTA FillApex and AH Plus

Physicochemical Properties and Surfaces Morphologies Evaluation of MTA FillApex and AH Plus

The bond strength of adhesive resins to AH plus contaminated dentin cleaned by various gutta-percha solvents

Comprehensive review of current endodontic sealers

Contact Info

Product

Resources

About