“…4,5 In recent years, ME has become one of the most promising technique to enhance the absorption of bioactive agents by various administration routes, such as oral, ocular, pulmonary, and nasal administrations. [6][7][8][9] In this study, the pseudo-ternary phase diagram was constructed and PUE-loaded ME formulation was optimized. The physicochemical properties of optimized ME formulation, such as morphology, droplet size, zeta potential, and solubility were characterized.…”