Evaluation of the composition of street cocaine seized in two regions of Brazil

Magalhães, Elisângela Jaqueline; Nascentes, Clésia C.; Pereira, Leandro S.A.; Guedes, Mário L.O.; Lordeiro, Rogério Araújo; Auler, Lúcia M.L.A.; Augusti, Rodinei; Queiroz, Maria Eliana Lopes Ribeiro de

doi:10.1016/j.scijus.2013.05.003

Cited by 51 publications

(40 citation statements)

References 22 publications

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“…A partir da composição das amostras de cocaína apreendidas no Brasil foi possível detectar que o principal adulterante encontrado em amostras oriundas do estado de Minas Gerais é a lidocaína, no Amazonas é a fenacetina, porém em amostras oriundas do Rio Grande do Sul a cocaína apresenta lidocaína e cafeína [20]; nesse mesmo estudo, os diluentes não são encontrados em grande parte das amostras oriundas do Amazonas, destacando assim as amostras do Rio Grande Sul que apresentou amostras diluídas em açucares e derivados [21].…”

Section: Principais Adulterantes E Diluentesunclassified

Abordagens metodológicas que auxiliam na identificação química da cocaína apreendida no Brasil

Freitas¹,

Silva²,

Barbosa³

2017

Rev. Bras. Crimin.

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ResumoO tráfico de drogas proscritas no Brasil tem aumentado consideravelmente. Um dos reflexos desse crescimento se dá pelo quantitativo apreendido pelos órgãos de segurança pública de drogas sintéticas, canabinóides e, em sua maioria, por cocaína. O Brasil encontra-se geograficamente localizado em uma área onde o cultivo de espécies da família Erythroxylaceae é beneficiado, além disso, faz fronteiras com os principais países produtores de cocaína no mundo, o que dificulta, sobremaneira, o combate ao seu tráfico. As polícias federal e civil têm identificado, constantemente, novos fornecedores e novos locais de refino de cocaína, logo, a identificação das rotas de tráfico, origem geográfica e dos seus distribuidores torna-se cada vez mais complexa exigindo dos órgãos de segurança pública e da comunidade forense em geral um melhor aprimoramento de suas metodologias de identificação e quantificação, de forma a fornecerem informações conclusivas para o combate ao seu tráfico. Assim, nesse trabalho, foram aval iadas as principais abordagens metodológicas que contribuem para a elucidação da identificação das amostras de cocaína apreendida no país.Palavras-Chave: Erythroxylum coca; Cocaína; Perfil químico. AbstractThe trafficking of banned drugs in Brazil has increased considerably. One of the consequences of this growth is the quantitative seized by public security organs of synthetic drugs, cannabinoids and, mostly cocaine. The Brazil is geographically located i n an area where the cultivation of Erythroxylaceae family species is benefited, moreover, it borders with major cocaine-producing countries in the world, making it difficult, exceedingly, combating their trafficking. The federal and civil polices have identified, constantly, new suppliers and new cocaine refining sites, so the identification of trafficking routes, geographical origin and its distributors becomes increasingly complex requiring law enforcement agencies and forensic community in general a better improvement of its identification and quantification methodologies in order to provide conclusive information to combat its trafficking. Thus, this study is intended to assess the main methodological approaches that contribute to the elucidation of the identification of cocaine samples seized in the country.

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Section: Principais Adulterantes E Diluentesunclassified

Abordagens metodológicas que auxiliam na identificação química da cocaína apreendida no Brasil

Freitas¹,

Silva²,

Barbosa³

2017

Rev. Bras. Crimin.

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“…Evaluation of the composition of street Cocaine seized in two regions of Brazil has also been recently reported. [26] In addition, attenuated total reflection infrared spectra of saliva samples have been recorded [27] with a particular interest in detecting Cocaine and measuring spectral interferences of selected diluents, masking agents, common medication, and soft drinks.…”

Section: Assessment Of the Selectivity Of Probe Xmentioning

confidence: 99%

Computational Design and Fabrication of Optical Fibre Fluorescent Chemical Probes for the Detection of Cocaine

Wren

Piletsky

Karim

et al. 2015

J. Lightwave Technol.

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This is the accepted version of the paper.This version of the publication may differ from the final published version. Abstract-A rationally designed fluorophore has been developed and has been incorporated into molecularly imprinted polymers, as the basis of the design of a sensor. Its use has allowed the fabrication of two different designs of fibre-optic chemical probes using an approach based on the change of the emitted fluorescence being related to the concentration of the desired species that was present. A high sensitivity to the drug Cocaine was achieved with each of the probes, showing positive changes in the fluorescence signal achieved in response to 1-100 μM solutions of the drug, in solution in aqueous acetonitrile. High sensitivity for Cocaine over a range of compounds was demonstrated for one of the probes (probe X) and detection of the drug is possible even in the presence of strong fluorescence interference. The work has also shown that probes of this type do not need to be discarded when used: re-use of probe X is possible using a straightforward washing procedure and the calibration performance was maintained. Permanent repository linkIndex Terms-Chemical probe, Cocaine probe, fluorescence, molecular imprinted polymer (MIP), optical fibre.

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“…Emergency department personnel are often tasked with identifying and treating the effects of not only the primary substances, but also any other compounds added to mimic or antagonize the main drug effects. [3,4] Furthermore, since cocaine and morphine (precursor of heroin) are both extracted from natural products, some impurities and minor alkaloids can be present in the final product. [1,2] Powdery drugs, such as cocaine and heroin, are frequently adulterated predominantly to obtain more doses and to increase the drug dealer's profits, although a range of modifications of the drug effects may also be observed.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, the consumed illicit drug may also simply be diluted with a range of substances, some of which could give rise to harmful synergic toxic actions. [3,4] The analysis of adulterants present in seized heroin and cocaine samples continues to be performed in several countries worldwide with the aim of tracing the routes of trafficking and adulteration for forensic purposes. [2] In the first case, inactive diluents are used, such as glucose, sodium carbonate, starch, and talc.…”

Section: Introductionmentioning

confidence: 99%