Evaluation of the diagnostic efficacy of liquid-based cytology obtained via percutaneous ultrasound-guided fine-needle aspiration for pancreatic masses: a large tertiary center’s 8-year experience

Yan, Xiaoyi; Zhou, Guili; Ji, Jiaqi; Gui, Yang; Chang, Xiaoyan; Zhang, Jing; Lv, Ke; Tan, Li

doi:10.1007/s00432-023-05438-y

J Cancer Res Clin Oncol

2023

DOI: 10.1007/s00432-023-05438-y

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Evaluation of the diagnostic efficacy of liquid-based cytology obtained via percutaneous ultrasound-guided fine-needle aspiration for pancreatic masses: a large tertiary center’s 8-year experience

Xiaoyi Yan,

Guili Zhou,

Jiaqi Ji

et al.

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2024

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Advances in diagnostic liquid‐based cytology

Abe,

Kawahara,

Akiba

et al. 2024

Cytopathology

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Liquid‐based cytology (LBC) has changed the landscape of gynaecological cytology. A growing demand exists for LBC in diagnostic cytology, particularly for ancillary testing, such as immunocytochemistry and molecular testing. Ancillary testing solely based on conventional preparation (CP) methods remains challenging. Recently, the increased demand for specialist testing and minimally invasive techniques, such as endoscopic ultrasonography fine‐needle aspiration, to obtain cellular samples has led to an increasing demand for ancillary testing on cytology LBC supernatant, slides and cell block (CB). This facilitates the diagnosis and prognosis in cytology samples enabling personalized treatment. An understanding of the history and future prospects of LBC is crucial for its application in routine diagnostics by cytopathologists and cytotechnologists. In this review, we initiated an internet search using the keyword ‘liquid‐based cytology’, and we conducted a literature review to discuss the usefulness of combined diagnosis of LBC and CP, immunocytochemistry and molecular testing and assessed the quality of nucleic acids in diagnostic LBC. High‐quality and cell‐rich diagnostic LBC surpassed the CP method alone in terms of reliability and versatility of ancillary testing in cytological diagnosis. Conclusively, diagnostic LBC lends itself to various new technologies and is expected to continue evolving with innovations in the future.

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Advances in diagnostic liquid‐based cytology

Abe,

Kawahara,

Akiba

et al. 2024

Cytopathology

View full text Add to dashboard Cite

show abstract

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Evaluation of the diagnostic efficacy of liquid-based cytology obtained via percutaneous ultrasound-guided fine-needle aspiration for pancreatic masses: a large tertiary center’s 8-year experience

Cited by 1 publication

References 32 publications

Advances in diagnostic liquid‐based cytology

Advances in diagnostic liquid‐based cytology

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