Evaluation of the dose-effect association between the number of doses and duration since the last dose of COVID-19 vaccine, and its efficacy in preventing the disease and reducing disease severity: A single centre, cross-sectional analytical study from India

Bhattacharya, Aakashneel; Ranjan, Piyush; Ghosh, Tapash Chandra; Agarwal, Harsh; Seth, S D; Maher, Ganesh; Upadhyay, Ashish Datt; Kumar, Arvind; Baitha, Upendra; Gupta, Gaurav; Prakash, Brahm; Dwivedi, Sada Nand; Wig, Naveet

doi:10.1016/j.dsx.2021.102238

Cited by 21 publications

(13 citation statements)

References 11 publications

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“…Benefits of vaccination outweigh its side effects especially for health care workers as they are at most risk due to continuous exposure [20]. Similar mild effects were experienced by Nepalese health care workers [21]. In our study younger population i.e.…”

Section: Resultssupporting

confidence: 70%

Post effects associated with SARS-CoV-2 vaccination among health care workers in Pakistan

Furqan

Naeem

Usman

et al. 2022

IJPHS

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The COVID-19 pandemic has witnessed the rapid development of vaccines produced simultaneously form various countries. However, these vaccines were shrouded by a set of myths ranging from serious effects to change of human DNA. Pakistan was one of the countries to start vaccination early and the front-line workers were first to be vaccinated. We undertook to study the vaccinated health care workers for the post effects of vaccines they received. The methodology adopted was through a structured questionnaire comprising 12 questions covering almost all the possible post effects. This was circulated among health care workers of Pak-Emirates Military hospital and Army Medical College/ National University of Medical Sciences, Rawalpindi, Pakistan. Fever was the most frequently encountered post effect, followed closely by pain at site of injection, headache and fatigue. There was a strong association between age and post effects of vaccination. No life threatening or serious side effects were experienced by health are workers indicating that benefits of vaccine outweigh its adverse effects especially with emergence of new variants. No participant required hospitalization following immunization. Therefore, vaccination against SARS-CoV-2 should be carried out on priority basis in order to avoid severe COVID-19 infection.<br /><br />

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Section: Resultssupporting

confidence: 70%

Post effects associated with SARS-CoV-2 vaccination among health care workers in Pakistan

Furqan

Naeem

Usman

et al. 2022

IJPHS

View full text Add to dashboard Cite

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“…The rapidly evolving COVID-19 has increased the difficulty of epidemic prevention and control. Through COVID-19 vaccination and other comprehensive measures, the spread of COVID-19 [ 12 ] and the occurrence of severe disease after SARS-CoV-2 infection can be effectively decreased [ 13 ]. Vaccination usually has certain benefits in reducing the risk of severe SARS-CoV-2 infection and fatality according to published literature [ 14 ], but there were still concerns about the potential harmfulness of COVID-19 vaccination in some patients with diabetes in China (56.4%) [ 15 ], Saudi Arabia (29.0%) [ 16 ], Malaysia (24.7%) [ 17 ] and Italy (14.2%) [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

The COVID-19 Vaccination Behavior and Correlates in Diabetic Patients: A Health Belief Model Theory-Based Cross-Sectional Study in China, 2021

et al. 2022

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The population with diabetes is more susceptible to severe acute respiratory syndrome-associated coronavirus (SARS-CoV)-2, and have a significantly higher coronavirus disease-2019 (COVID-19) mortality rate. Previous studies have shown low willingness for the COVID-19 vaccination, and there are limited reports on the behavior and relevance of the COVID-19 vaccination. This study aimed to determine the uptake behavior and associated factors of the COVID-19 vaccine. In our cross-sectional questionnaire-based clinical study, 645 diabetes patients affiliated with two affiliated hospitals of Changzhi Medical College completed the questionnaire between June to October 2021. The health belief model (HBM) was used in examining factors influencing vaccination behavior. After adjusting for covariates with significant differences in social background characteristics, a multivariable logistic regression was used to determine predictors related to uptake in COVID-19 vaccination. A total of 162 vaccinated and 483 unvaccinated eligible diabetic patients were recruited. Patients who believed that the COVID-19 syndrome is severe (aOR3.67, 95%CI 1.88–7.17; p < 0.001), believe that vaccination can significantly reduce the risk of SARS-Cov-2 infection (aOR3.48, 95%CI 1.80–6.73; p < 0.001), believe that vaccination is beneficial to themselves and others (aOR 4.53, 95%CI 1.71–11.99; p = 0.002), think that relatives’ vaccination status has a positive impact on their vaccination behavior (aOR 5.68, 95%CI 2.83–11.39; p < 0.001), and were more likely to be vaccinated; worrying about the adverse health effects of COVID-19 vaccination (aOR 0.18, 95%CI 0.09–0.35; p < 0.001) was negatively correlated with COVID-19 vaccination behavior. Health care workers should provide targeted informative interventions based on the safety and protective effects theory of HBM to improve vaccination behavior in patients with diabetes.

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“…COVID-19 vaccines were produced after considerable research and clinical studies, and they were licensed early for emergency use due to the severity of the issue [ 5 ]. Many lives have been saved due to the COVID-19 vaccination, which has significantly reduced hospital admissions compared to the non-vaccinated population [ 6 ]. Over 118 million have been vaccinated among the Pakistani populace, which makes up about 57% of the whole population [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of COVID-19 Vaccination on Menstrual Cycle: A Cross-Sectional Study From Karachi, Pakistan

Sualeh¹,

Uddin²,

Junaid³

et al. 2022

Cureus

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BackgroundThe coronavirus disease 2019 (COVID-19) disease triggered a worldwide health catastrophe. To deal with this deadly situation multiple vaccines were developed and a mass immunization program started globally. However, vaccine hesitancy was seen, especially among women of reproductive age, having concerns that the vaccine might affect their menstrual cycle. This study investigated the link between COVID-19 vaccination and menstrual abnormalities. It is essential for us to understand the effects of vaccines on menstruation as menstrual distress can have effects on everyday life, and mental and reproductive health. MethodsA cross-sectional study was performed using self-administered online forms to collect data from all over Karachi. The sample included 384 females aged 18 years and above. The data were collected from November 2021 to February 2022. ResultsMajority of the participants were aged 21 years and had a normal body mass index (BMI). Most were moderately stressed (n=245) with 146 reporting menstrual changes post-vaccination. The difference between the post-vaccine menstruation affected (n=146) and the unaffected cohort (n=238) was significant. Other factors which likely contributed to the post-vaccine menstrual changes included Perceived Stress Scale (PSS) score, strenuous physical activity, and the pre-vaccine menstrual flow. ConclusionsAmong the women vaccinated for COVID-19, strenuous physical activity and high perceived stress levels affected the menstrual cycle. There is no denying that existing data are inadequate, which is one of the grounds for vaccination apprehension, particularly among menstruating women. To minimize this hesitation, the spread of disinformation about the vaccine's influence on the menstrual cycle must be avoided. In future research and clinical trials, menstruation-related side effects should also be investigated when developing vaccines.

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Evaluation of the dose-effect association between the number of doses and duration since the last dose of COVID-19 vaccine, and its efficacy in preventing the disease and reducing disease severity: A single centre, cross-sectional analytical study from India

Cited by 21 publications

References 11 publications

Post effects associated with SARS-CoV-2 vaccination among health care workers in Pakistan

Post effects associated with SARS-CoV-2 vaccination among health care workers in Pakistan

The COVID-19 Vaccination Behavior and Correlates in Diabetic Patients: A Health Belief Model Theory-Based Cross-Sectional Study in China, 2021

Impact of COVID-19 Vaccination on Menstrual Cycle: A Cross-Sectional Study From Karachi, Pakistan

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