Evaluation of the echocardiogram as an epidemiologic tool in an asymptomatic population.

Valdez, Riccardo; Motta, Jorge; London, E; Martin, Randolph P.; Haskell, W. L.; Farquhar, John W.; Popp, Richard L.; Horlick, L.

doi:10.1161/01.cir.60.4.921

Cited by 66 publications

(23 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…8,14 -18 Ladipo et al, 14 evaluating measurements of 10 blind duplicated tracings by 3 observers, reported intraobserver mean absolute difference of 0.7 to 1.2, 0.2 to 0.8, 0.3 to 0.4, and 0.4 to 0.8 mm for diastolic and systolic LV diameters, diastolic LV posterior wall thickness, and diastolic interventricular septal thickness, respectively. Having 3 investigators measure 7 ventricular parameters of 20 randomly selected echocardiograms twice, Valdez et al 16 showed that significant intraobserver difference was found in only 1 person in the measurement of end-diastolic LV posterior wall thickness. Small means and SDs of intraobserver differences in our study (Table 1) showed that each technician read the same echocardiograms consistently the second time, achieving a high degree of agreement.…”

Section: Discussionmentioning

confidence: 99%

“…8,[15][16][17][18] De Leonardis and Cinelli 15 compared measurements of aortic root diameter, left atrial diameter, end-diastolic septal and posterior wall thicknesses, and end-diastolic and end-systolic LV diameters by 2 experienced interpreters on 50 routinely performed M-mode echocardiograms and concluded that no significant interobserver variability was found for all measured echocardiographic parameters. Valdez et al 16 found statistically significant differences in measurements of enddiastolic septal thickness, end-diastolic and end-systolic LV posterior wall thicknesses, and end-diastolic and end-systolic LV diameters by 3 observers on 20 echocardiograms. The maximum mean difference was 2 mm.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Validity of Echocardiographic Measurement in an Epidemiological Study

et al. 1999

View full text Add to dashboard Cite

Abstract-In Project HeartBeat!, a longitudinal study of cardiovascular disease risk factors in healthy children and adolescents, 3 samples of 40, 80, and 182 echocardiograms, respectively, were randomly selected and reread to evaluate intraobserver and interobserver variabilities and comparability between measurements of field echocardiographic technicians and reference readings at Texas Children's Hospital. Included in the evaluation were 8 M-mode echocardiographic measurements, ie, aortic root diameter, left atrial diameter, and end-diastolic and end-systolic measurements of interventricular septal thickness, left ventricular (LV) diameter, and LV posterior wall thickness; 8 Doppler measurements; and a calculated LV mass. Means and SDs of the differences of the paired measurements were used to assess the relative bias and random error of the measurements. For the intraobserver comparison, means and SDs of the differences were very small, indicating that the echo measurements were performed consistently by each project echo technician. Interobserver comparison showed statistically but not clinically significant differences between the paired readings of end-diastolic septal thickness, end-systolic LV posterior wall thickness, and 5 Doppler measurements.Comparison with reference readings at Texas Children's Hospital showed significant differences in diastolic LV diameter, systolic septal thickness, and right ventricular ejection time. These differences, however, were minimal with limited clinical significance. Mean differences in LV mass for the corresponding comparisons were -1.82, 4.50, and 0.0013 g, and the SDs were 18.79, 24.16, and 12.35 g, respectively. We conclude that the echocardiographic measurements taken from healthy children in a longitudinal study can be made accurately with acceptable reproducibility. (Hypertension. 1999;34:236-241.)

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Validity of Echocardiographic Measurement in an Epidemiological Study

et al. 1999

View full text Add to dashboard Cite

show abstract

“…20 In an evaluation of hypertensive subjects participating in the Systolic Hypertension in the Elderly Program (SHEP), Pearson et al found significantly increased LV mass and LA index. 21 Here we have shown the high association of LV hypertrophy and LA enlargement in patients aged 2 60.…”

Section: Left Atrial Enlargement and Hypertensionmentioning

confidence: 99%

Left atrial size in 164 hypertensive patients: An echocardiographic and ambulatory blood pressure study

Tedesco¹,

Salvo²,

Ratti³

et al. 2001

Clinical Cardiology

View full text Add to dashboard Cite

SummaryBcickground: Left atrial enlargement (LAE) is associated with an increased risk of death and cardiovascular (CV) hospitalization. Whether or not LAE reflects early structural change from hypertension is unclear.Hyporlwsis: The aim of this study was to evaluate the relationship between LA size, 24-h blood pressure measurements, age. body mass index (BMI), and left ventricular mass index (LVMI) in hypertensive patients.Mer110d.s: We studied 164 outpatients (age range 30-76 years, 73 men and 91 women) with mild to moderate hypertension. Physical examination, electrocardiogram, noninvasive blood pressure monitoring (ABPM), Doppler echocardiograin were performed. Left ventricular mass index and LA dimensions were calculated. The sample was divided by age (< 60 and 2 60 years).Resrlrs: Left ventricular hypertrophy (LVH) was present in 45% of patients aged < 60 years and in 70% of patients aged 260 years (p = 0.002). Left atrial enlargement (>4 cm) was present in 35% of elderly and in 24% of young patients (p = 0.3 I ), and in 36% of patients with and 2 I % of patients without LVH (p = 0.0057). There was no significant difference in the younger patients with and without LVH. The incidence of obesity was low (3 1 %) in the whole sample.

show abstract

“…All available studies agree that LV mass should be indexed by body size, of which body surface area appears to be the best measure by a narrow margin. 4 Similarly, the three largest echocardiographic studies of normal subjects 3 -*•' have found that LV mass indexed by body surface area differs significantly between men and women, and the primary LV measurements reported by Valdez et al 12 . are in accord with this conclusion.…”

mentioning

confidence: 91%

Left ventricular hypertrophy in hypertension. Prevalence and relationship to pathophysiologic variables.

Devereux¹,

Pickering²,

Alderman³

et al. 1987

Hypertension

View full text Add to dashboard Cite

SUMMARY In less than a decade since development of echocardiographic measurement of left ventricular muscle mass, studies using this technique have provided considerable information about the prevalence and pathophysiology of left ventricular hypertrophy in human hypertension. Increased left ventricular mass has been found in a significant minority of patients with systemic hypertension, with the exact prevalence dependent both on how a population is selected and on the sex, race, and possibly age composition of its members. All published studies have reported that left ventricular hypertrophy is more closely related to blood pressure recorded in the patient's natural setting during normal activity or exercise -whether measured by portable recorder or home manometer -than to blood pressure measured by the physician. In addition, studies indicate that the classic hypertensive abnormalities of concentric left ventricular hypertrophy and increased peripheral resistance are interrelated, while left ventricular hypertrophy is absent in a subgroup of patients with mild essential hypertension who exhibit high cardiac output and evidence of supernormal myocardial contractility. Conversely, the left ventricular functional response to exercise is inversely related to the degree of hypertrophy. High levels of blood viscosity, which would tend to blunt the reduction in peripheral resistance expected during sleep or exercise, have also been associated with left ventricular hypertrophy in patients with essential hypertension. Echocardiographic studies have provided evidence both for and against the hypothesis that activity of the sympathetic or reninangiotensin systems plays a direct role in causing hypertensive cardiac hypertrophy. These findings demonstrate the useful role that echocardiographic assessment of left ventricular structure and function may play in hypertension research. patients with systemic hypertension -being both a J necessary adaptation to pump a normal amount of blood against the increased pressure load and a pathologic manifestation of hypertensive cardiovascular disease. For many years, knowledge of the complex status of the heart in human hypertension advanced slowly because of the lack of suitable means of measuring cardiac anatomy and function in unselected hypertensive patients or of following their natural history. The development over the last decade of accurate echocardiographic methods for detection of LVH and characterization of ventricular contractile performance has catalyzed an explosion of information about the heart in hypertension.

show abstract

Evaluation of the echocardiogram as an epidemiologic tool in an asymptomatic population.

Cited by 66 publications

References 21 publications

Validity of Echocardiographic Measurement in an Epidemiological Study

Validity of Echocardiographic Measurement in an Epidemiological Study

Left atrial size in 164 hypertensive patients: An echocardiographic and ambulatory blood pressure study

Left ventricular hypertrophy in hypertension. Prevalence and relationship to pathophysiologic variables.

Contact Info

Product

Resources

About