Evaluation of the effect of lidocaine epidural injection on immunological indices in dogs under total intravenous anesthesia submitted to ovariohysterectomy

Rastabi, Hadi Imani; Khosravi, Mohammad; Moslemi, Maryam

doi:10.1371/journal.pone.0253731

Cited by 4 publications

(1 citation statement)

References 39 publications

(50 reference statements)

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“…The advantage of using this route of administration is the possibility of blocking the modulation and transmission of nociceptive signals in the spinal cord, providing anaesthesia and analgesia of the dermatomes located in the caudal abdominal regions. Therefore, the epidural technique is particularly suitable for ovariectomy and ovariohysterectomy surgeries [ 55 ]. The meninges are composed of the dura mater, arachnoid membrane, and pia mater.…”

Section: Local Anaestheticsmentioning

confidence: 99%

Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description

Cicirelli

Burgio

Lacalandra

et al. 2022

Animals

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Canine ovariectomy is an elective surgery with a moderate level of pain. Despite its relative simplicity, it requires surgical pain management. This study aimed to collect all recent information about local and regional anaesthetic/analgesic techniques in a review of the literature describing the technique utilised. The various procedures described in this review use local anaesthetics to improve analgesia in the routine systemic anaesthetic protocol. The approach described in this paper is called multimodal analgesia and is used in addition to the normal standard anaesthetic protocol. These techniques proved effective in minimising responses to the surgical stimulus and ensured adequate intraoperative and postoperative analgesia. The routine use of multimodal analgesia is considered a useful alternative for pain management in canine ovariectomy, in that it minimises patient suffering, improves the recovery of rescue analgesia, increases drug savings, and improves animal outcomes. In addition, the use of these local and regional techniques ensures satisfactory analgesic coverage that lasts for the first hours postoperatively.

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Section: Local Anaestheticsmentioning

confidence: 99%

Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description

Cicirelli

Burgio

Lacalandra

et al. 2022

Animals

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The impact of the transversus abdominis plane block (TAP) on stress response measured through the complete blood– derived inflammatory markers

Espadas-González,

Usón-Casaús,

Pastor-Sirvent

et al. 2023

Vet Res Commun

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This study aims to evaluate the effect of the transversus abdominis plane (TAP) block on the blood cells and the inflammatory markers neutrophil– to– lymphocyte ratio (NLR), platelet– to– lymphocyte ratio (PLR), and systemic immune– inflammation index (SII) after the laparoscopic ovariectomy (LapOV) in dogs. 72 healthy bitches undergoing LapOV were randomly allocated to the no– TAP group of dogs under inhaled anesthesia (IA), the TAP– S group (IA and TAP with saline), and the TAP– B group (IA and TAP with bupivacaine). The NLR, PLR, and SII were calculated 1 h before ovariectomy (T0) and at 2−3 h (T1), 6−8 h (T2), and 20−24 h (T3) post– surgery. The number of dogs requiring postoperative analgesic rescue with buprenorphine and the doses administered in each group were recorded. Significant changes were observed in all groups’ postoperative NLR, PLR, and SII over time. Between groups, no differences were observed in any of the ratios at any control point (NLR at T0−T3: p = 0.17, 0.36, 0.80, and 0.95; PLR at T0−T3: p = 0.70, 0.62, 0.21, 0.87; SII at T0−T3: p = 0.29, 0.65, 0.09, and 0.34). A significantly lower number of dogs required analgesic rescue in the TAP-B group (p = 0.0001) and a lower number of doses were administered (p = 0.001). There is no difference in the inflammatory response measured through the complete blood– derived inflammatory markers after the LapOV in dogs when the postoperative pain is managed entirely with opioids or with the TAP block with bupivacaine. The hydrodissection associated with the TAP block technique does not increase the inflammatory response.

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Effects and mechanisms of perioperative medications on the hypothalamic pituitary adrenal response to surgical injury: A narrative review

Feng,

Chang,

Liu

et al. 2024

Journal of Clinical Anesthesia

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Evaluation of the effect of lidocaine epidural injection on immunological indices in dogs under total intravenous anesthesia submitted to ovariohysterectomy

Cited by 4 publications

References 39 publications

Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description

Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description

The impact of the transversus abdominis plane block (TAP) on stress response measured through the complete blood– derived inflammatory markers

Effects and mechanisms of perioperative medications on the hypothalamic pituitary adrenal response to surgical injury: A narrative review

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