Evaluation of the effect of intra-articular injection of macrolide antibiotics versus corticosteroids on internal derangement of temporomandibular joint.

Abstract

Internal derangement is a broad term that encompassesmore than simply a disc displacement.It also involves inflammation, changes in the articular surfaces, alteration in joint pressure and synovial fluid. Furthermore, it includes production of biochemical substances and factors as oxidative stresses due to clenching and parafunctions. Production of reactive Oxygen species (ROS) has