Evaluation of the effect of collagen stabilizing agents like chitosan and proanthocyanidin on the shear bond strength to dentin and microleakage of resin composite at enamel and cemental walls: An in vitro study

Nivedita, Lukram; Prakash, Venkatachalam; Mitthra, Suresh; Mary, Newbegin Selvakumar Gold Pearlin; Alagarsamy, V.; Subbiya, Arunajatesan

doi:10.4103/jcd.jcd_195_20

Cited by 13 publications

(6 citation statements)

References 18 publications

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“…Dentin biomodifiers alter the structure of collagen fibrils improving their degradation resistance, and when used as pre-treatment prior to the bonding procedures aid in increasing the bond strength values [ 38 39 ]. However, Fialho et al .…”

Section: Discussionmentioning

confidence: 99%

Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

et al. 2023

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Objectives Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin. Materials and Methods The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05). Results At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months ( p = 0.009) for marginal adaptation and postoperative sensitivity ( p = 0.029), but no significant difference were verified between treatments ( p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%. Conclusions The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria.

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Section: Discussionmentioning

confidence: 99%

Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

et al. 2023

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“…Bonding to dentin, is a great challenge due to difference in structural and chemical composition of dentin. Some of which include eradication of smear layer, formation of hybrid layer, enzymatic breakdown of collagen [11]. The percentage of collagen fibrils decreases as we proceed from superficial to deep dentin.…”

Section: Discussionmentioning

confidence: 99%

“…Proanthocyanidin interacts with proteins and increases the Type I collagen cross-linking by promoting hydrogen bond formation between protein amide carbonyl and the phenolic hydroxyl groups [11].…”

Section: Discussionmentioning

confidence: 99%

“…Chitosan solution (Panvo Organics Ltd, Chennai, India) with a degree of acetylation >85% was prepared by dissolving 10 mg in 1 ml of 1% acetic acid (Sisco Research Laboratories-SRL, Mumbai, India) using a magnetic stirrer for 2 h at the rate of 50 rpm at room temperature to bring to a concentration of 1% Chitosan acetate [11].…”

Section: Preparation Of Solutionsmentioning

confidence: 99%

“…Chitosan is a hydrophilic biopolymer (2-amino-2-deoxy-β-dglucopyranose) with more number of free hydroxyl and amino groups that have the capability to form crosslinks with other reactive molecules. The free reactive groups present in the chitosan interacts with collagen to form chemical bonds [11].…”

Section: Introductionmentioning

confidence: 99%

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Impact of Various Cross Linking Agents on Dentin Adhesive Systems - an In-vitro Study

Prasanna

Rajasekhar

Battu

et al. 2021

JPRI

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Aims and Objectives: The main aim of this study is to compare and evaluate the shear bond strength of composite resin using a total etch adhesive and self-etch adhesive after treatment with different collagen cross-linking agents. Materials and Methods: Forty freshly extracted human maxillary central incisors were taken. The proximal dentin was exposed, cavities were prepared on mesial and distal of each tooth. The specimens were randomly divided into two groups based on bonding agent applied-Group A and Group B i.e universal bonding agent and all in one bonding agent respectively and are subdivided into four groups based on the surface treatment of dentin. Group I A (n=10) Control-total etch(CTE); Group II A (n=10) Sodium Ascorbate-total etch (STE); Group III A (n=10)- Proanthocyanidin total etch(PTE); Group IV A (n=10)- Chitosan total etch (CHTE); Group I B (n=10) Control-self etch (CSE); Group II B (n=10) Sodium Ascorbate-self etch(SSE); Group III B (n=10)- Proanthocyanidin self-etch (PSE); and Group IV B (n=10) - Chitosan self-etch (CHSE). Shear bond strength of the specimens are tested with universal testing machine, and the data was statistically analysed with one way ANOVA. Results: Significantly higher shear bond strength to dentin was observed in teeth treated with 6.5% Proanthocyanidin Total etch, 10% Sodium Ascorbate Total etch and 1% Chitosan acetate compared to the control group. No significant difference was seen with self-etch treated groups. Conclusion: Dentin surface pretreatment with 6.5% Proanthocyanidin, 10% Sodium Ascorbate and 1% Chitosan acetate results in significant enhancement in bond strength of composite resin to deep dentin.

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Does dentin pretreatment with chitosan improve the bond strength of restorative material? A systematic review and meta-analysis of in vitro studies

Alves,

Cerqueira,

Candemil

et al. 2024

International Journal of Adhesion and Adhesives

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Evaluation of the effect of collagen stabilizing agents like chitosan and proanthocyanidin on the shear bond strength to dentin and microleakage of resin composite at enamel and cemental walls: An in vitro study

Cited by 13 publications

References 18 publications

Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

Impact of Various Cross Linking Agents on Dentin Adhesive Systems - an In-vitro Study

Does dentin pretreatment with chitosan improve the bond strength of restorative material? A systematic review and meta-analysis of in vitro studies

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