Evaluation of the effectiveness of the use of Postacnetin gel in the therapy of the postacne symptom complex using the device ANTERA 3D

Abstract

Background. The postacne symptom complex occurs in the outcome of vulgar acne in 40% of cases. Recently, there has been a tendency to grow up acne. Currently, there are many methods in the arsenal of a dermatologist and a cosmetologist for correcting post-acne elements, but most of the procedures for correcting postacne elements have age restrictions, some of the procedures are accompanied by severe pain and the presence of a rehabilitation period, and the economic component of these procedures is also of great importance. Therefore, for the treatment of the post-acne symptom complex, there should be methods that are highly effective and accessible to patients. In most cases, the assessment of the clinical effectiveness of treatment is subjective, both for the doctor and for the patient. Photo documentation is also not in all cases a reliable way to represent the quality and effectiveness of treatment. Consequently, the use of hardware methods for quantifying the severity of disease indicators to confirm the effectiveness of treatment increases the patient's compliance.
 Aims. Evaluation of the effectiveness of Postacnetin gel in the treatment of postacne symptom complex, using the ANTERA 3D device.
 Materials and methods. 12 patients aged 18 to 28 years with the presence of postacne symptoms were under observation. The study was conducted on the basis of the Department of Dermatovenereology of SibSMU and the medical center Estetik in Tomsk. During the entire study period, patients applied Postacnetin gel to one half of the face. Treatment regimen: Postaknetin gel was applied in a thin layer, point-by-point on the postakne elements 2 times a day. The duration of treatment was 28 days. To assess the clinical effectiveness, photo documentation, three-dimensional analysis of the skin surface on the ANTERA 3D device and statistical analysis were performed.
 Results. The average level of redness in 12 patients on the side of using Postacnetin gel before the study was 117.200 0.424, 1 month after using the gel, there was a significant decrease in the level of the indicator to 95.900 0.849 (р 0.05). The average value of the pigmentation level before using the Postacnetin gel and 1 month after use was 56.950 0.919 and 46.600 0.424, respectively (р 0.05). This indicates a significant decrease in the level of pigmentation. The average value of the volume index before the study was 9.350 0.212, after 28 days the volume index decreased to 6.750 0.071, respectively (р 0.05).
 Conclusions. As a result of the conducted research, it was established with the help of the ANTERA 3D device that the use of Postacne gel for 28 days leads to a regression of the indicators of postacne elements.