Evaluation of the effectiveness of vaginal misoprostol to induce first trimester abortion

Bugalho, António; Faúndes, Aníbal; Jamisse, Luisa; Usfá, M.; Maria, E. Johansson; Bique, Cassimo

doi:10.1016/0010-7824(96)00044-3

Cited by 73 publications

(32 citation statements)

References 10 publications

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“…In most studies misoprostol is administered vaginally, as this is more effective than oral administration. [8][9][10][11][12][13][14][15][16] A number of clinical trials have sought to determine the optimal regimen for use of misoprostol alone. [17][18][19] In July 2003, an expert meeting on misoprostol was held in Washington DC, resulting in a consensus statement on use of misoprostol alone for abortion induction in pregnancies up to nine weeks (63 days) LMP.…”

Section: Introductionmentioning

confidence: 99%

Misoprostol Alone for Early Medical Abortion in a Latin American Clinic Setting

Billings¹

2004

Reproductive Health Matters

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Misoprostol is being used widely by women throughout Latin America, often based on instructions passed along through friends, acquaintances or professionals who may have little information about safe and effective use. This paper presents the experience of a Latin American clinic working in a legally restrictive setting that offers misoprostol as one option to women seeking early pregnancy termination. Between February 2001 and June 2002, 3,225 women who attended the clinic chose to use misoprostol rather than vacuum aspiration. 89.9% returned for follow-up, of whom 76.4% had had a complete abortion within 72 hours, using one, two or three doses of 800 micrograms of misoprostol administered by the woman herself vaginally every 24 hours. The first 78 women who returned for follow-up at 72 hours responded to a questionnaire regarding their experiences. Satisfaction with the abortion process was high, despite some pain, chills, diarrhoea and/or nausea. Seventy-two of the 78 women said they would use misoprostol again if they needed to terminate another pregnancy and would recommend it to a friend. Having a clinic where staff are knowledgeable and experienced in misoprostol use is particularly important in settings where abortion is stigmatised, unsafe abortion common and access to safe services limited. A 2004 Reproductive Health Matters. All rights reserved.

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Section: Introductionmentioning

confidence: 99%

Misoprostol Alone for Early Medical Abortion in a Latin American Clinic Setting

Billings¹

2004

Reproductive Health Matters

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“…1,2 Misoprostol, a prostaglandin E 1 analogue, is widely prescribed for the prevention and treatment of gastric ulcers that may result from long-term use of nonsteroidal anti-inflammatory drugs (NSAID). Misoprostol has also been used to induce abortion [2][3][4][5][6][7][8][9][10] and has the advantage of being cheap, easily stored and readily available.…”

Section: Introductionmentioning

confidence: 99%

Intravaginal 400 μg misoprostol for pregnancy termination in cases of blighted ovum: a randomised controlled trial

Kovavisarach

Sathapanachai

2002

Aust NZ J Obst Gynaeco

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“…Studies show that compounds like antiprogesterones and prostaglandins can be safely used. The prostaglandin E 1 (PGE 1 ) analogue misoprostol can be administered by various routes with minimal side effects and has high efficacy rates (1)(2)(3)(4). A Cochrane review in 2004 (5) described misoprostol in a dose of 800 mg was more effective than any other prostaglandin.…”

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confidence: 99%